Cardizem and Actifed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cardizem (diltiazem hydrochloride) and Actifed (pseudoephedrine hydrochloride; triprolidine hydrochloride). Common drug interactions include anxiety among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Cardizem and Actifed. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Cardizem?

Cardizem has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 28,014 Cardizem users. Check the latest studies of Cardizem.

What is Actifed?

Actifed has active ingredients of pseudoephedrine hydrochloride; triprolidine hydrochloride. It is often used in allergies. eHealthMe is studying from 1,091 Actifed users. Check the latest studies of Actifed.

On Jul, 29, 2026

14 people who take Cardizem and Actifed together, and have interactions are studied.

What are the common drug interactions of Cardizem and Actifed, by gender? *:

female:

Anxiety
Asthenia (weakness)
Atrioventricular block first degree (heart block first degree)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Breast cancer
Cardiac disorder
Cardiac failure congestive
Cellulitis (infection under the skin)
Cerebral haematoma (collection of blood in brain)

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Fall
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dyspnoea (difficult or laboured respiration)
Failure to thrive (inadequate weight gain and physical growth in children)
Myalgia (muscle pain)
Myopathy (a muscular disease in which the muscle fibres do not function)
Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain

What are the common drug interactions of Cardizem and Actifed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cerebral haematoma (collection of blood in brain)
Cerebral haemorrhage (bleeding within the brain)
Cerebral ventricle dilatation (enlargement of ventricle of brain)
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Distractibility (inability to sustain one's attention)
Embolic stroke (stroke due to obstruction due to an embolus)
Facial paresis (weakness in facial muscle movement)
Fatigue (feeling of tiredness)
Gait disturbance

50-59:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Asthma
Atrioventricular block second degree (heart block second degree)
Breast cancer
Cardiac failure congestive
Chemical poisoning
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Fall
Dyspnoea (difficult or laboured respiration)
Failure to thrive (inadequate weight gain and physical growth in children)
Myalgia (muscle pain)
Myopathy (a muscular disease in which the muscle fibres do not function)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain

What are the existing conditions these people have? *

High Blood Cholesterol: 5 people, 35.71%
Wound: 2 people, 14.29%
Swelling: 2 people, 14.29%
Sleep Disorder: 2 people, 14.29%
Oedema (fluid collection in tissue): 2 people, 14.29%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 7.14%
Menopausal Symptoms: 1 person, 7.14%
Chest Wall Pain: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Cardizem and Actifed?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously