Cardizem and Perforomist drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cardizem (diltiazem hydrochloride) and Perforomist (formoterol fumarate). Common drug interactions include palpitations among females and bacterial infection among males.

The phase IV clinical study analyzes what interactions people have when they take Cardizem and Perforomist. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Cardizem?

Cardizem has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 28,014 Cardizem users. Check the latest studies of Cardizem.

What is Perforomist?

Perforomist has active ingredients of formoterol fumarate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 1,431 Perforomist users. Check the latest studies of Perforomist.



On Jul, 05, 2026

36 people who take Cardizem and Perforomist together, and have interactions are studied.

Cardizem and Perforomist drug interactions.

What are the common drug interactions of Cardizem and Perforomist, by gender? *:

female:

  1. Palpitations (feelings or sensations that your heart is pounding or racing)
  2. Parainfluenzae virus infection
  3. Respiratory disorder (respiratory disease)
  4. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  5. Sinusitis (inflammation of sinus)
  6. Pneumonia
  7. Upper limb fracture
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Cystitis (inflammation of the wall of the bladder)
  10. Drug ineffective

male:

  1. Bacterial infection
  2. Bladder cancer
  3. White blood cell count decreased

What are the common drug interactions of Cardizem and Perforomist, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Asthma
  2. Pancreatitis acute (sudden inflammation of pancreas)
  3. Pharyngeal erythema (pharyngeal redness)
  4. Rhinitis allergic (inflammation of the nasal airways due to allergy)

40-49:

n/a

50-59:

  1. Abdominal discomfort
  2. Anaphylactic reaction (serious allergic reaction)
  3. Asthma
  4. Blood potassium decreased
  5. Depression
  6. Drug ineffective
  7. Dyspnoea (difficult or laboured respiration)
  8. Headache (pain in head)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

60+:

  1. Fatigue (feeling of tiredness)
  2. Herpes zoster
  3. Palpitations (feelings or sensations that your heart is pounding or racing)
  4. Sinusitis (inflammation of sinus)
  5. Upper limb fracture
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Cystitis (inflammation of the wall of the bladder)
  8. Drug hypersensitivity
  9. Pneumonia
  10. Drug ineffective

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 8 people, 22.22%
  2. Primary Immunodeficiency Syndrome: 7 people, 19.44%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 16.67%
  4. Idiopathic Thrombocytopenic Purpura (Itp) (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 4 people, 11.11%
  5. Asthma: 4 people, 11.11%
  6. Pain: 3 people, 8.33%
  7. Muscle Spasms (muscle contraction): 3 people, 8.33%
  8. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 5.56%
  9. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 2 people, 5.56%
  10. Bacteraemia (presence of bacteria in the blood): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Cardizem and Perforomist?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cardizem and Perforomist:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cardizem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Perforomist:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cardizem and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Perforomist and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diltiazem hydrochloride and formoterol fumarate (the active ingredients of Cardizem and Perforomist, respectively), and Cardizem and Perforomist (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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