Carpine and Hydrocodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Carpine (pilocarpine hydrochloride) and Hydrocodone (hydrocodone bitartrate; ibuprofen). Common drug interactions include oxygen saturation decreased among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Carpine and Hydrocodone. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Carpine?

Carpine has active ingredients of pilocarpine hydrochloride. eHealthMe is studying from 5,561 Carpine users. Check the latest studies of Carpine.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

On Jul, 07, 2026

28 people who take Carpine and Hydrocodone together, and have interactions are studied.

Carpine and Hydrocodone drug interactions.

What are the common drug interactions of Carpine and Hydrocodone, by gender? *:

female:

Oxygen saturation decreased
Fatigue (feeling of tiredness)
Fall
Headache (pain in head)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Influenza
Joint injury
Limb injury
Neck pain
Pain

male:

Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Multiple fractures
Osteopenia (a condition where bone mineral density is lower than normal)
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Renal failure (kidney dysfunction)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Anxiety
Bone density decreased
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Carpine and Hydrocodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Psoriasis (immune-mediated disease that affects the skin)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Gastric bypass
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

50-59:

Fatigue (feeling of tiredness)
Pain
Arthralgia (joint pain)
Asthenia (weakness)
Back disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Dizziness
Dry eye (lack of adequate tears)
Dry mouth

60+:

Fall
Pyrexia (fever)
Cough
Diarrhoea
Disability
Dyspnoea (difficult or laboured respiration)
Ear infection
Fatigue (feeling of tiredness)
Fungal infection
Gingivitis (inflammation of gums)

What are the existing conditions these people have? *

Asthma: 6 people, 21.43%
Pain: 5 people, 17.86%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 17.86%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 17.86%
Stress And Anxiety: 4 people, 14.29%
Dry Mouth: 4 people, 14.29%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 14.29%
High Blood Cholesterol: 4 people, 14.29%
Neuralgia (pain in one or more nerves): 4 people, 14.29%
Depression: 4 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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