Caspofungin acetate and Protonix drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Caspofungin acetate (caspofungin acetate) and Protonix (pantoprazole sodium). Common drug interactions include salivary hypersecretion among females and colitis among males.
The phase IV clinical study analyzes what interactions people have when they take Caspofungin acetate and Protonix. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Caspofungin acetate?
Caspofungin acetate has active ingredients of caspofungin acetate. eHealthMe is studying from 1,724 Caspofungin acetate users. Check the latest studies of Caspofungin acetate.
What is Protonix?
Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.
12 people who take Caspofungin acetate and Protonix together, and have interactions are studied.

What are the common drug interactions of Caspofungin Acetate and Protonix, by gender? *:
female:
- Salivary hypersecretion (excess saliva secretion)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Septic shock (shock due to blood infection)
- Sinus bradycardia (an unusually slow heartbeat due to heart disease)
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
- Sinusitis (inflammation of sinus)
- Skin turgor decreased (less elasticity of skin)
- Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
- Death
- Haematochezia (passage of stools containing blood)
male:
- Colitis (inflammation of colon)
- Diarrhoea
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bradycardia (abnormally slow heart action)
- Enterococcal infection
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Intravascular haemolysis (intravascular rupture of red blood cells with the release of haemoglobin and the cellular constituents into the plasma, or liquid portion of whole blood)
- Multi-organ failure (multisystem organ failure)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
What are the common drug interactions of Caspofungin Acetate and Protonix, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Salivary hypersecretion (excess saliva secretion)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Septic shock (shock due to blood infection)
- Sinus bradycardia (an unusually slow heartbeat due to heart disease)
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
- Sinusitis (inflammation of sinus)
- Skin turgor decreased (less elasticity of skin)
- Slow response to stimuli (slow response by nerves)
- Spinal osteoarthritis (joint cartilage loss in spine)
- Supplementation therapy
60+:
- Colitis (inflammation of colon)
- Diarrhoea
- Infection
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Acute myocardial infarction (acute heart attack)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bradycardia (abnormally slow heart action)
- Cardiac disorder
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Diarrhoea haemorrhagic (bloody diarrhoea)
What are the existing conditions these people have? *
- Stress And Anxiety: 2 people, 16.67%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 16.67%
- Malignant Melanoma (skin cancer rises from melancytes): 2 people, 16.67%
- Pneumonia Cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses): 1 person, 8.33%
- Pain: 1 person, 8.33%
- Nausea (feeling of having an urge to vomit): 1 person, 8.33%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
- Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 1 person, 8.33%
- Discomfort: 1 person, 8.33%
- Cardiac Disorder: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Caspofungin acetate and Protonix?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Caspofungin acetate (1,724 reports)
- Protonix (132,658 reports)
Browse all drug interactions of Caspofungin acetate and Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Caspofungin acetate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Caspofungin acetate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Protonix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Biswal S, "Complete heart block in a neutropenic patient with aspergillosis: An unusual adverse effect of caspofungins", Journal of pharmacology & pharmacotherapeutics, 2012 Jan .
- Biswal S, "Complete heart block in a neutropenic patient with aspergillosis: An unusual adverse effect of caspofungins", Journal of pharmacology & pharmacotherapeutics, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on caspofungin acetate and pantoprazole sodium (the active ingredients of Caspofungin acetate and Protonix, respectively), and Caspofungin acetate and Protonix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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