Caspofungin acetate and Vfend drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Caspofungin acetate (caspofungin acetate) and Vfend (voriconazole). Common drug interactions include septic shock among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Caspofungin acetate and Vfend. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Caspofungin acetate?

Caspofungin acetate has active ingredients of caspofungin acetate. eHealthMe is studying from 1,724 Caspofungin acetate users. Check the latest studies of Caspofungin acetate.

What is Vfend?

Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.



On Jul, 14, 2026

14 people who take Caspofungin acetate and Vfend together, and have interactions are studied.

Caspofungin acetate and Vfend drug interactions.

What are the common drug interactions of Caspofungin Acetate and Vfend, by gender? *:

female:

  1. Septic shock (shock due to blood infection)
  2. Acute lymphocytic leukaemia (cancer of the white blood cells)
  3. Blood pressure increased
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Diarrhoea
  6. Epistaxis (bleed from the nose)
  7. Haematemesis (vomiting of blood)
  8. Nausea (feeling of having an urge to vomit)
  9. Oral candidiasis (fungal infection of mouth)
  10. Pain in extremity

male:

  1. Arthralgia (joint pain)
  2. Back pain
  3. Blood lactate dehydrogenase increased
  4. Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  7. Disturbance in attention
  8. Eosinophil count decreased
  9. Eosinophil percentage decreased
  10. Epstein-barr virus infection

What are the common drug interactions of Caspofungin Acetate and Vfend, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Acute lymphocytic leukaemia (cancer of the white blood cells)
  2. Arthralgia (joint pain)
  3. Back pain
  4. Blood pressure increased
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Diarrhoea
  7. Epistaxis (bleed from the nose)
  8. Haematemesis (vomiting of blood)
  9. Nausea (feeling of having an urge to vomit)
  10. Oral candidiasis (fungal infection of mouth)

20-29:

  1. Fungal endocarditis (fungal infection of the inner layer of the heart)

30-39:

  1. Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant)
  2. Alanine aminotransferase increased
  3. Aplasia (defective development or congenital absence of an organ or tissue)
  4. Aspartate aminotransferase increased
  5. Blood bilirubin increased
  6. Blood lactate dehydrogenase increased
  7. Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  10. Disturbance in attention

40-49:

n/a

50-59:

n/a

60+:

  1. Adverse event
  2. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  3. Hepatic failure (liver failure)
  4. Septic shock (shock due to blood infection)
  5. Stem cell transplant
  6. Altered state of consciousness (altered state of mind)
  7. Bacteraemia (presence of bacteria in the blood)
  8. Pneumonia
  9. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

What are the existing conditions these people have? *

  1. Fungal Infection: 3 people, 21.43%
  2. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 21.43%
  3. Sinusitis (inflammation of sinus): 1 person, 7.14%
  4. Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 7.14%
  5. Nausea (feeling of having an urge to vomit): 1 person, 7.14%
  6. Infection: 1 person, 7.14%
  7. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 7.14%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%
  9. Fungal Endocarditis (fungal infection of the inner layer of the heart): 1 person, 7.14%
  10. Candidiasis (candidiasis or thrush is a fungal infection): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Caspofungin acetate and Vfend:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Caspofungin acetate:

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Browse all side effects of Vfend:

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Browse all interactions between Caspofungin acetate and drugs from A to Z:

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Browse all interactions between Vfend and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on caspofungin acetate and voriconazole (the active ingredients of Caspofungin acetate and Vfend, respectively), and Caspofungin acetate and Vfend (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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