Cataflam and Depakote drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cataflam (diclofenac potassium) and Depakote (divalproex sodium). Common drug interactions include diarrhoea among females and injection site erythema among males.

The phase IV clinical study analyzes what interactions people have when they take Cataflam and Depakote. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Cataflam?

Cataflam has active ingredients of diclofenac potassium. It is often used in pain. eHealthMe is studying from 1,851 Cataflam users. Check the latest studies of Cataflam.

What is Depakote?

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 55,581 Depakote users. Check the latest studies of Depakote.

On Jul, 20, 2026

14 people who take Cataflam and Depakote together, and have interactions are studied.

Cataflam and Depakote drug interactions.

What are the common drug interactions of Cataflam and Depakote, by gender? *:

female:

Diarrhoea
Anxiety
Drug dependence
Abdominal distension
Bedridden
Hyperhidrosis (abnormally increased sweating)
Muscle spasms (muscle contraction)
Platelet count decreased
Rectal haemorrhage (bleeding from anus)
Suicidal ideation

male:

Injection site erythema (redness at injection site)
Injection site inflammation
Drug dependence
Hallucination (an experience involving the perception of something not present)
Hepatic function abnormal
Hostility
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Suicide attempt
Injection site pain
Injection site pruritus (severe itching at injection site)

What are the common drug interactions of Cataflam and Depakote, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diarrhoea
Abdominal distension
Muscle spasms (muscle contraction)
Rectal haemorrhage (bleeding from anus)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Arthralgia (joint pain)
Crying
Defaecation urgency (a sudden compelling urge to defecate)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug addiction

40-49:

Injection site inflammation
Bedridden
Hyperhidrosis (abnormally increased sweating)
Platelet count decreased
White blood cell count decreased
Injection site erythema (redness at injection site)
Injection site pain
Injection site pruritus (severe itching at injection site)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

50-59:

Anxiety
Enuresis (repeated inability to control urination)
Erythema (redness of the skin)
Gait disturbance
Injection site haemorrhage (bleeding from injection site)
Peripheral swelling
Suicidal ideation

60+:

Anxiety
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Migraine (headache)
Rash macular (small, flat red spots)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Skin discolouration (change of skin colour)
Dizziness
Eye irritation

What are the existing conditions these people have? *

Stress And Anxiety: 3 people, 21.43%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 21.43%
Back Pain: 2 people, 14.29%
Sleep Disorder: 2 people, 14.29%
Depression: 2 people, 14.29%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.14%
Dyskinesia (abnormality or impairment of voluntary movement): 1 person, 7.14%
Gastric Disorder (disease of stomach): 1 person, 7.14%
Headache (pain in head): 1 person, 7.14%
High Blood Cholesterol: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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