Cataflam and Ibu drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cataflam (diclofenac potassium) and Ibu (ibuprofen). Common drug interactions include rash among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Cataflam and Ibu. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Cataflam?

Cataflam has active ingredients of diclofenac potassium. It is often used in pain. eHealthMe is studying from 1,851 Cataflam users. Check the latest studies of Cataflam.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

On Jul, 16, 2026

42 people who take Cataflam and Ibu together, and have interactions are studied.

What are the common drug interactions of Cataflam and Ibu, by gender? *:

female:

Rash
Renal failure (kidney dysfunction)
Swelling
Urinary retention (the inability to completely or partially empty the bladder)
Vomiting
Weakness
Abdominal discomfort
Abdominal pain upper
Adverse drug reaction
Anaemia (lack of blood)

male:

Abdominal pain upper
Completed suicide (act of taking one's own life)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Arteriosclerosis (thickening and hardening of arteries)
Asthenia (weakness)
Atrioventricular block first degree (heart block first degree)
Bradycardia (abnormally slow heart action)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Cardiac failure congestive

What are the common drug interactions of Cataflam and Ibu, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Blood alkaline phosphatase increased
Blood bilirubin decreased
Blood lactate dehydrogenase increased
Cough
Dysphagia (a condition in which swallowing is difficult or painful)
Eating disorder
Lymphocyte count decreased
Mean cell volume increased (more than normal average red blood cell volume)
Monocyte count increased
Platelet count increased

20-29:

Abortion spontaneous (naturally occurring miscarriage)
Asthenia (weakness)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Drug hypersensitivity
Eating disorder
Face oedema (swelling of face)
Fatigue (feeling of tiredness)
Lethargy (tiredness)
Nausea (feeling of having an urge to vomit)
Oedema lower limb (fluid collection in tissue of lower leg)

30-39:

Application site erythema (redness of the skin at application site)
Application site pain
Application site rash
Application site swelling
Application site vesicles (small bubble within a cell at application site)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Completed suicide (act of taking one's own life)
Depression
Drug ineffective

40-49:

Drug hypersensitivity
Abdominal pain
Cardiovascular disorder (heart diseases)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cerebrovascular disorder (disease of brain)
Chest pain
Chronic kidney disease
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)

50-59:

Chronic kidney disease
Abdominal pain
Angioedema (rapid swelling of the dermis)
Ear disorder
Epistaxis (bleed from the nose)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Idiopathic thrombocytopenic purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)
Malaise (a feeling of general discomfort or uneasiness)
Migraine (headache)
Myasthenic syndrome (a group of conditions characterized by muscle weakness (myasthenia) that worsens with physical exertion)

60+:

Drug ineffective
Dysgeusia (disorder of the sense of taste)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Pruritus (severe itching of the skin)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Urticaria (rash of round, red welts on the skin that itch intensely)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

What are the existing conditions these people have? *

Depression: 9 people, 21.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 14.29%
Nausea And Vomiting: 5 people, 11.90%
Intervertebral Disc Degeneration (spinal disc degeneration): 5 people, 11.90%
High Blood Pressure: 5 people, 11.90%
Glossitis (infection of tongue with soreness): 5 people, 11.90%
Dissociative Disorder: 5 people, 11.90%
Stress And Anxiety: 4 people, 9.52%
Sleep Disorder: 4 people, 9.52%
Insomnia (sleeplessness): 4 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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