Cataflam and Protonix drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cataflam (diclofenac potassium) and Protonix (pantoprazole sodium). Common drug interactions include renal cancer among females and injury among males.
The phase IV clinical study analyzes what interactions people have when they take Cataflam and Protonix. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.
What is Cataflam?
Cataflam has active ingredients of diclofenac potassium. It is often used in pain. eHealthMe is studying from 1,851 Cataflam users. Check the latest studies of Cataflam.
What is Protonix?
Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.
33 people who take Cataflam and Protonix together, and have interactions are studied.

What are the common drug interactions of Cataflam and Protonix, by gender? *:
female:
- Renal cancer (cancer of kidney)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Subdural haemorrhage (bleeding between the skull and the surface of the brain)
- Upper respiratory tract infection
- Vomiting
- Wound infection
- Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
- Cardiogenic shock (inadequate circulation of blood)
- Device related infection
- Dyspnoea (difficult or laboured respiration)
male:
- Injury
- Adnexa uteri mass (ovarian cysts)
- Decreased interest
- Depression
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
- Dyspepsia (indigestion)
- Ear pain
- Exostosis (formation of new bone on the surface of a bone)
- Fatigue (feeling of tiredness)
What are the common drug interactions of Cataflam and Protonix, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Abdominal pain upper
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Injury
20-29:
- Electrocardiogram qt prolonged
- Electrocardiogram repolarisation abnormality
- Electrocardiogram st-t change
- Gangrene (body tissue dies)
- Hyperkinesia (higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic drugs)
- Hypoxia (low oxygen in tissues)
- Injury
- Mitral valve incompetence (inefficient heart valve)
- Myalgia (muscle pain)
- Peripheral vascular disorder
30-39:
- Drug ineffective
- Ear discomfort
- Ear pain
- Nausea (feeling of having an urge to vomit)
- Psoriasis (immune-mediated disease that affects the skin)
- Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
40-49:
- Chronic kidney disease
- Productive cough
50-59:
- Blindness unilateral
- Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Asthma
- Autoimmune hepatitis
- Haematocrit decreased
- Haematoma (collection of blood outside the blood vessels)
- Haemoglobin decreased
- Injection site haematoma (localized swelling filled with blood at injection site)
60+:
n/a
What are the existing conditions these people have? *
- High Blood Pressure: 9 people, 27.27%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 18.18%
- Inflammation: 4 people, 12.12%
- Sleep Disorder: 3 people, 9.09%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 9.09%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 9.09%
- Neuropathy Peripheral (surface nerve damage): 3 people, 9.09%
- High Blood Cholesterol: 3 people, 9.09%
- Dyspnea (difficult or laboured breathing): 2 people, 6.06%
- Bone Disorder: 2 people, 6.06%
* Approximation only. Some reports may have incomplete information.
Do you take Cataflam and Protonix?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cataflam and Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cataflam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cataflam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Protonix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on diclofenac potassium and pantoprazole sodium (the active ingredients of Cataflam and Protonix, respectively), and Cataflam and Protonix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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