Catapres-tts-1 and Bextra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Catapres-tts-1 (clonidine) and Bextra (valdecoxib). Common drug interactions include breast mass among females and adjustment disorder with depressed mood among males.
The phase IV clinical study analyzes what interactions people have when they take Catapres-tts-1 and Bextra. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Catapres-tts-1?
Catapres-tts-1 has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 2,047 Catapres-tts-1 users. Check the latest studies of Catapres-tts-1.
What is Bextra?
Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.
12 people who take Catapres-tts-1 and Bextra together, and have interactions are studied.

What are the common drug interactions of Catapres-Tts-1 and Bextra, by gender? *:
female:
- Breast mass
- Coronary artery stenosis (narrowing of coronary artery)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dyspepsia (indigestion)
- Dyspnoea (difficult or laboured respiration)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Nausea (feeling of having an urge to vomit)
- Oedema peripheral (superficial swelling)
male:
- Adjustment disorder with depressed mood
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Drug dependence
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Dyspnoea (difficult or laboured respiration)
- Fall
- Fatigue (feeling of tiredness)
- Feeling cold
- Hypersomnia (excessive daytime sleepiness (eds))
- Hypoaesthesia (reduced sense of touch or sensation)
What are the common drug interactions of Catapres-Tts-1 and Bextra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anxiety
- Oxygen saturation decreased
- Panic attack
- Post procedural cellulitis (post procedural bacterial infection of the skin and soft tissues)
- Dyspnoea (difficult or laboured respiration)
- Nausea (feeling of having an urge to vomit)
- Depression
- Hypersomnia (excessive daytime sleepiness (eds))
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Speech disorder
50-59:
- Alopecia (absence of hair from areas of the body)
- Breast cancer female
- Breast mass
60+:
- Anaemia (lack of blood)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Chest pain
- Coronary artery stenosis (narrowing of coronary artery)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Renal failure acute (rapid kidney dysfunction)
- Tooth infection
What are the existing conditions these people have? *
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 25.00%
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 16.67%
- Stomach Discomfort (pain in abdomen): 2 people, 16.67%
- Seasonal Allergy (allergic condition due to certain season): 2 people, 16.67%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 16.67%
- Hot Flush (sudden feelings of heat): 2 people, 16.67%
- Heart Rate Irregular: 2 people, 16.67%
- Depression: 2 people, 16.67%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 16.67%
- Constipation: 2 people, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Catapres-tts-1 and Bextra?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Catapres-tts-1 (2,047 reports)
- Bextra (20,994 reports)
Browse all drug interactions of Catapres-tts-1 and Bextra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Catapres-tts-1:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Bextra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Catapres-tts-1 and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bextra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on clonidine and valdecoxib (the active ingredients of Catapres-tts-1 and Bextra, respectively), and Catapres-tts-1 and Bextra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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