Catapres and Azithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Catapres (clonidine hydrochloride) and Azithromycin (azithromycin). Common drug interactions include hypotension among females and vomiting among males.

The phase IV clinical study analyzes what interactions people have when they take Catapres and Azithromycin. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Catapres?

Catapres has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 6,680 Catapres users. Check the latest studies of Catapres.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

50 people who take Catapres and Azithromycin together, and have interactions are studied.

Catapres and Azithromycin drug interactions.

What are the common drug interactions of Catapres and Azithromycin, by gender? *:

female:

Hypotension (abnormally low blood pressure)
Intervertebral disc protrusion (spinal disc protrusion)
Onychomycosis (fungal infection of the nail)
Polysubstance dependence
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Skin fissures (a crack in the skin)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
Type 2 diabetes mellitus
Xerosis (abnormal dryness of the skin or mucus membranes)

male:

Vomiting
Nausea (feeling of having an urge to vomit)
Depression
Hyperlipidaemia (presence of excess lipids in the blood)
Pneumonia
Ventricular fibrillation (abnormally irregular heart rhythm)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Haematocrit decreased
Haemoglobin decreased

What are the common drug interactions of Catapres and Azithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Appetite disorder (abnormal eating habits)
Depression
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Rash

20-29:

n/a

30-39:

Anxiety
Emotional distress
Pain
Pericardial effusion (fluid around the heart)
Pericarditis (inflammation of the pericardium)
Peroneal nerve palsy
Pleuritic pain
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary oedema (fluid accumulation in the lungs)
Abdominal pain

40-49:

Cellulitis (infection under the skin)
Nausea (feeling of having an urge to vomit)
Vomiting
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Asthma
Back pain
Chest pain
Confusional state
Dehydration (dryness resulting from the removal of water)
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)

50-59:

Chest pain
Headache (pain in head)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pericardial effusion (fluid around the heart)
Presyncope
Renal failure chronic (long lasting kidney dysfunction)
Asthenia (weakness)
Diabetic gastroparesis (paralysis of the muscles of the stomach caused by diabetes)
Dyspnoea (difficult or laboured respiration)
Unresponsive to stimuli

60+:

Chronic kidney disease
Abdominal discomfort
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrioventricular block first degree (heart block first degree)
Blood cholesterol increased
Blood triglycerides increased
Breast cyst
Cardiac failure congestive
Cardiac murmur (an heart sound in valve abnormality)
Cardiovascular disorder (heart diseases)

What are the existing conditions these people have? *

Cardiac Disorder: 11 people, 22.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 16.00%
Stress And Anxiety: 7 people, 14.00%
Pain: 7 people, 14.00%
Hiv Infection: 7 people, 14.00%
Diabetes: 7 people, 14.00%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 12.00%
Postpartum Depression (depression suffered by a mother following childbirth): 6 people, 12.00%
Infection: 6 people, 12.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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