Catapres and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Catapres (clonidine hydrochloride) and Melatonin (melatonin). Common drug interactions include back pain among females and drug dependence among males.

The phase IV clinical study analyzes what interactions people have when they take Catapres and Melatonin. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Catapres?

Catapres has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 6,680 Catapres users. Check the latest studies of Catapres.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

On Aug, 03, 2026

82 people who take Catapres and Melatonin together, and have interactions are studied.

Catapres and Melatonin drug interactions.

What are the common drug interactions of Catapres and Melatonin, by gender? *:

female:

Back pain
Hallucination (an experience involving the perception of something not present)
Anaemia (lack of blood)
Chills (felling of cold)
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Depression
Gait disturbance
Oedema peripheral (superficial swelling)
Syncope (loss of consciousness with an inability to maintain postural tone)

male:

Drug dependence
Respiratory depression (respiration has a rate below 12 breaths)
Victim of child abuse
Abnormal weight gain
Alopecia (absence of hair from areas of the body)
Atelectasis (partial or complete collapse of the lung)
Chronic kidney disease
Cushingoid (obesity and weakening of the muscles)
Drug abuse
Drug clearance decreased

What are the common drug interactions of Catapres and Melatonin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Hallucination (an experience involving the perception of something not present)
Abnormal behaviour
Agitation (state of anxiety or nervous excitement)
Somnolence (a state of near-sleep, a strong desire for sleep)
Diarrhoea
Pneumonia
Abdominal pain
Aggression
Anxiety
Asthenia (weakness)

10-19:

Drug dependence
Respiratory depression (respiration has a rate below 12 breaths)
Child abuse
Drug ineffective
Epidural lipomatosis (excessive accumulation of fat within the epidural space -brain)
Juvenile idiopathic arthritis (a subset of arthritis seen in childhood)
Obesity (having too much body fat)
Victim of child abuse
Abnormal weight gain
Alopecia (absence of hair from areas of the body)

20-29:

Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Fatigue (feeling of tiredness)
Myalgia (muscle pain)
Rash
Hypertrichosis (hair growth on the body in an amount considered abnormal)
Joint swelling
Oedema (fluid collection in tissue)

30-39:

Drug ineffective
Fatigue (feeling of tiredness)
Headache (pain in head)
Asthma
Back pain
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Coeliac disease (simple food intolerance)
Constipation
Drug hypersensitivity
Drug intolerance (drug sensitivity)

40-49:

Hypohidrosis (lack of sweating)
Swelling face
Abdominal pain upper
Arthralgia (joint pain)
Asthenia (weakness)
Bedridden
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cushingoid (obesity and weakening of the muscles)
Depression
Diarrhoea

50-59:

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Cardiac disorder
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease
Cytomegalovirus colitis (an inflammation of the colon from virus)
Diarrhoea
Diastolic dysfunction
Fall
Foot fracture
Hemiparesis (weakness on one side of the body)

60+:

Dyspnoea (difficult or laboured respiration)
Myalgia (muscle pain)
Pain
Syncope (loss of consciousness with an inability to maintain postural tone)
Vision blurred
Abdominal discomfort
Abdominal distension
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Back pain

What are the existing conditions these people have? *

Pain: 17 people, 20.73%
Wheezing (a high-pitched whistling sound made while you breath): 9 people, 10.98%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 9.76%
Stress And Anxiety: 7 people, 8.54%
Nausea (feeling of having an urge to vomit): 7 people, 8.54%
Itching: 7 people, 8.54%
Constipation: 7 people, 8.54%
Sleep Disorder: 6 people, 7.32%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 7.32%
Muscle Spasms (muscle contraction): 6 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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