Catapres and Zyprexa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Catapres (clonidine hydrochloride) and Zyprexa (olanzapine). Common drug interactions include dysfunctional uterine bleeding among females and head injury among males.

The phase IV clinical study analyzes what interactions people have when they take Catapres and Zyprexa. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Catapres?

Catapres has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 6,680 Catapres users. Check the latest studies of Catapres.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,724 Zyprexa users. Check the latest studies of Zyprexa.

On Jul, 15, 2026

93 people who take Catapres and Zyprexa together, and have interactions are studied.

What are the common drug interactions of Catapres and Zyprexa, by gender? *:

female:

Dysfunctional uterine bleeding
Ear pain
Headache (pain in head)
Local swelling (swelling at the site of some application of substance or injury)
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Respiratory disorder (respiratory disease)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Homicidal ideation (thoughts about human killing another human)
Pancreatitis (inflammation of pancreas)

male:

Head injury
Aggression
Injury
Pain
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Abnormal behaviour
Anger
Bone pain
Brain injury
Bruxism (habitual grinding of the teeth, typically during sleep)

What are the common drug interactions of Catapres and Zyprexa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Agitation (state of anxiety or nervous excitement)
Hallucination (an experience involving the perception of something not present)
Lymphocyte count decreased
Monocyte count increased
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Hostility
Hyperkinetic syndrome (attention deficit disorder)

10-19:

Cystitis (inflammation of the wall of the bladder)

20-29:

Head injury
Aggression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Suicidal ideation
Abnormal behaviour
Agitation (state of anxiety or nervous excitement)
Anger
Bone pain
Brain injury
Bruxism (habitual grinding of the teeth, typically during sleep)

30-39:

Head injury
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Aggression
Tremor (trembling or shaking movements in one or more parts of your body)
Suicidal ideation
Hyperhidrosis (abnormally increased sweating)
Agitation (state of anxiety or nervous excitement)
Confusional state
Dyspnoea (difficult or laboured respiration)
Fall

40-49:

Alanine aminotransferase increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Type 2 diabetes mellitus
Anaemia (lack of blood)
Aspartate aminotransferase increased
Blood glucose increased
Hepatic enzyme increased
Pancreatitis acute (sudden inflammation of pancreas)
Staphylococcal bacteraemia (a bacterial infection of blood)
Subclavian vein thrombosis (abnormal condition in which a clot develops within the subclavian or axillary vein)

50-59:

Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Cardiac failure congestive
Completed suicide (act of taking one's own life)
Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperkalaemia (damage to or disease of the kidney)

60+:

Headache (pain in head)
Death
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Confusional state
Drug dependence
Faecal incontinence (a lack of control over passing stool)
Fall
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pneumonia
Urinary incontinence (inability to control the flow of urine and involuntary urination)

What are the existing conditions these people have? *

Depression: 22 people, 23.66%
Pain: 15 people, 16.13%
Stress And Anxiety: 12 people, 12.90%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 12 people, 12.90%
Insomnia (sleeplessness): 12 people, 12.90%
Agitation (state of anxiety or nervous excitement): 8 people, 8.60%
Mood Swings (an extreme or rapid change in mood): 7 people, 7.53%
Psychotic Disorder: 6 people, 6.45%
Sleep Disorder: 5 people, 5.38%
Hypersensitivity: 5 people, 5.38%

* Approximation only. Some reports may have incomplete information.

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