Cefazolin and Adcirca drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefazolin (cefazolin sodium) and Adcirca (tadalafil). Common drug interactions include bronchitis among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Cefazolin and Adcirca. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

What is Adcirca?

Adcirca has active ingredients of tadalafil. It is often used in pulmonary hypertension. eHealthMe is studying from 54,957 Adcirca users. Check the latest studies of Adcirca.

On Aug, 01, 2026

100 people who take Cefazolin and Adcirca together, and have interactions are studied.

Cefazolin and Adcirca drug interactions.

What are the common drug interactions of Cefazolin and Adcirca, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dyspnoea (difficult or laboured respiration)
Nasopharyngitis (inflammation of the nasopharynx)
Chest discomfort
Pain
Weight increased
Atelectasis (partial or complete collapse of the lung)
Cardioversion
Dizziness
Procedural pain

male:

Pneumonia
Hypoxia (low oxygen in tissues)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Rash
Thrombocytopenia (decrease of platelets in blood)
Diarrhoea
Sepsis (a severe blood infection that can lead to organ failure and death)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Adenoidal hypertrophy (enlarged adenoids)
Biliary colic

What are the common drug interactions of Cefazolin and Adcirca, by age (0-1 to 60+)? *:

0-1:

Adenoidal hypertrophy (enlarged adenoids)
Erythromelalgia (episodes of pain, redness, and swelling in various parts of the body)
Femur fracture
Pneumonia
Hypoxia (low oxygen in tissues)
Anaemia (lack of blood)
Catheter site erythema (redness of skin at catheter site)
Chylothorax (collection of lymph fluid around the lung)
Diarrhoea
Erythema (redness of the skin)

2-9:

Hypoxia (low oxygen in tissues)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Device related infection
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Pneumonia

10-19:

Diarrhoea
Headache (pain in head)
Nasopharyngitis (inflammation of the nasopharynx)
Platelet count decreased
Procedural pain
Procedural vomiting
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting
Device related infection
Catheter site infection (infection at the site of insertion)

20-29:

Headache (pain in head)
Platelet count decreased
Alanine aminotransferase increased
Aspartate aminotransferase increased
Diarrhoea
Pulmonary alveolar haemorrhage (acute bleeding)
Liver disorder (liver diseases)
Oxygen saturation decreased
Pulmonary oedema (fluid accumulation in the lungs)
Atelectasis (partial or complete collapse of the lung)

30-39:

Anaemia (lack of blood)
Device related infection
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardioversion
Syncope (loss of consciousness with an inability to maintain postural tone)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Pneumonia
Rash
Right ventricular failure (right half of the heart fails to work)

40-49:

Nausea (feeling of having an urge to vomit)
Device dislocation
Device related infection
Pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Haemorrhagic diathesis (bleeding tendency)
Prurigo (chronic skin disease causing severe itching)
Pyrexia (fever)
Stitch abscess (pus in stitches)

50-59:

Oxygen saturation decreased
Secretion discharge
Vomiting
Brain neoplasm (tumour of brain)
Dizziness
Malaise (a feeling of general discomfort or uneasiness)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Gait disturbance
Immobile (not moving)

60+:

Right ventricular failure (right half of the heart fails to work)
Renal impairment (severely reduced kidney function)
Brain natriuretic peptide increased
Chronic gastritis (long lasting infection of stomach lining)
Craniotomy
Depression
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Headache (pain in head)
Hepatic enzyme increased
Hypokalaemia (low potassium)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 94 people, 94.00%
Hypokalemia (low potassium): 31 people, 31.00%
Right Ventricular Failure (right half of the heart fails to work): 25 people, 25.00%
Cardiac Failure: 19 people, 19.00%
Device Related Infection: 17 people, 17.00%
Fever: 15 people, 15.00%
Diarrhea: 14 people, 14.00%
Sedation: 13 people, 13.00%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 10 people, 10.00%
Anaemia (lack of blood): 9 people, 9.00%

* Approximation only. Some reports may have incomplete information.

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