Cefazolin and Bifidobacterium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefazolin (cefazolin sodium) and Bifidobacterium (bifidobacteria). Common drug interactions include toxic epidermal necrolysis among females and urinary tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Cefazolin and Bifidobacterium. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

What is Bifidobacterium?

Bifidobacterium has active ingredients of bifidobacteria. eHealthMe is studying from 5,013 Bifidobacterium users. Check the latest studies of Bifidobacterium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

33 people who take Cefazolin and Bifidobacterium together, and have interactions are studied.

Cefazolin and Bifidobacterium drug interactions.

What are the common drug interactions of Cefazolin and Bifidobacterium, by gender? *:

female:

Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Device related infection
Abdominal distension
Abdominal pain
Catheter site infection (infection at the site of insertion)
Cough
Pyrexia (fever)
Diarrhoea
Erythema (redness of the skin)
Headache (pain in head)

male:

Urinary tract infection
Abdominal abscess (collection of pus in abdomen)
Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Cytomegalovirus infection
Gastroenteritis eosinophilic (white blood cell deposits in tissue of stomach or intestine with infection)
Otitis media acute (rapid inflammation of the middle ear)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Selenium deficiency (lack of selenium)
Suture rupture

What are the common drug interactions of Cefazolin and Bifidobacterium, by age (0-1 to 60+)? *:

0-1:

Renal failure (kidney dysfunction)

2-9:

Urinary tract infection
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Cytomegalovirus infection
Gastroenteritis eosinophilic (white blood cell deposits in tissue of stomach or intestine with infection)
Otitis media acute (rapid inflammation of the middle ear)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Selenium deficiency (lack of selenium)
Viral upper respiratory tract infection
Zinc deficiency

10-19:

n/a

20-29:

Cough
Diarrhoea
Epistaxis (bleed from the nose)
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Hyperthyroidism (over activity of the thyroid gland)
Device occlusion

30-39:

Cardiac failure
Catheter related infection
Cystitis bacterial (inflammation of the wall of the bladder by bacteria escherichia coli)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic nephropathy (diabetic kidney disease)
Gangrene (body tissue dies)
Hallucination (an experience involving the perception of something not present)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Nasopharyngitis (inflammation of the nasopharynx)
Palpitations (feelings or sensations that your heart is pounding or racing)

40-49:

Device related infection
Abdominal distension
Abdominal pain
Pyrexia (fever)
Stomatitis (inflammation of mucous membrane of mouth)
Subileus

50-59:

Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Catheter site infection (infection at the site of insertion)
Erythema (redness of the skin)
Abdominal pain
Arthralgia (joint pain)
Back pain
Blood potassium decreased
Blood pressure decreased
Catheter site erythema (redness of skin at catheter site)
Chest pain

60+:

Pyrexia (fever)
Abdominal abscess (collection of pus in abdomen)
Small intestinal obstruction (blockage in small intestine)
Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)
Subcutaneous abscess
Suture rupture
Upper respiratory tract inflammation
Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Device related infection

What are the existing conditions these people have? *

Sedation: 9 people, 27.27%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 8 people, 24.24%
Pneumonia: 6 people, 18.18%
High Blood Pressure: 6 people, 18.18%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 15.15%
Anaesthesia: 4 people, 12.12%
Urination - Excessive Volume: 4 people, 12.12%
Thermal Burn (burn by heat): 4 people, 12.12%
Gastric Ulcer (stomach ulcer): 4 people, 12.12%
Urinary Tract Infection: 3 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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