Cefazolin and Efavirenz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefazolin (cefazolin sodium) and Efavirenz (efavirenz). Common drug interactions include pancytopenia among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Cefazolin and Efavirenz. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

What is Efavirenz?

Efavirenz has active ingredients of efavirenz. It is often used in hiv infection. eHealthMe is studying from 15,501 Efavirenz users. Check the latest studies of Efavirenz.



On Jul, 16, 2026

19 people who take Cefazolin and Efavirenz together, and have interactions are studied.

Cefazolin and Efavirenz drug interactions.

What are the common drug interactions of Cefazolin and Efavirenz, by gender? *:

female:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Osteonecrosis (death of bone)
  4. Osteoporosis (bones weak and more likely to break)
  5. Perianal abscess
  6. Renal failure (kidney dysfunction)
  7. Renal injury (kidney injury)
  8. Renal mass (mass in kidney)
  9. Skeletal injury (bone and supporting muscle injury)
  10. Tooth loss

What are the common drug interactions of Cefazolin and Efavirenz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cytomegalovirus infection
  2. Gastrointestinal disorder (functional problems of gastrointestinal tract)

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Emotional distress
  5. Pain
  6. Depression
  7. Appetite disorder (abnormal eating habits)
  8. Asthenia (weakness)
  9. Back pain
  10. Diarrhoea

50-59:

n/a

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Wrist fracture
  4. Ankle fracture
  5. Bone density decreased
  6. Upper limb fracture
  7. Emotional distress
  8. Osteopenia (a condition where bone mineral density is lower than normal)
  9. Pain
  10. Clavicle fracture

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 3 people, 15.79%
  2. Neuropathy Peripheral (surface nerve damage): 3 people, 15.79%
  3. Eye Pain: 3 people, 15.79%
  4. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 15.79%
  5. Analgesic Effect: 3 people, 15.79%
  6. Orchitis (inflammation of the testes): 3 people, 15.79%
  7. Pain: 3 people, 15.79%
  8. Fungal Infection: 2 people, 10.53%
  9. Bacterial Infection: 2 people, 10.53%
  10. Bone Disorder: 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Cefazolin and Efavirenz?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cefazolin and Efavirenz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cefazolin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Efavirenz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefazolin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Efavirenz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cefazolin sodium and efavirenz (the active ingredients of Cefazolin and Efavirenz, respectively), and Cefazolin and Efavirenz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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