Cefazolin and Renagel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefazolin (cefazolin sodium) and Renagel (sevelamer hydrochloride). Common drug interactions include anhedonia among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Cefazolin and Renagel. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

What is Renagel?

Renagel has active ingredients of sevelamer hydrochloride. eHealthMe is studying from 8,246 Renagel users. Check the latest studies of Renagel.



On Jul, 09, 2026

55 people who take Cefazolin and Renagel together, and have interactions are studied.

Cefazolin and Renagel drug interactions.

What are the common drug interactions of Cefazolin and Renagel, by gender? *:

female:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Death
  3. Emotional distress
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Renal impairment (severely reduced kidney function)
  6. Renal injury (kidney injury)
  7. Vasculitis (inflammation of a blood vessel or blood vessels)
  8. Fear
  9. Injury
  10. Oedema peripheral (superficial swelling)

male:

  1. Anaemia (lack of blood)
  2. Hypotension (abnormally low blood pressure)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Oedema peripheral (superficial swelling)
  6. Thrombocytopenia (decrease of platelets in blood)
  7. Arrhythmia (irregular heartbeat)
  8. Cough
  9. Oedema (fluid collection in tissue)
  10. Pyrexia (fever)

What are the common drug interactions of Cefazolin and Renagel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
  2. Visual acuity reduced (reduced clearness of vision)

10-19:

n/a

20-29:

  1. Bone marrow failure
  2. Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
  3. Scotoma (an area of diminished vision within the visual field)
  4. Thyroid neoplasm (tumour of thyroid)
  5. Vasculitis (inflammation of a blood vessel or blood vessels)
  6. Abasia (inability to walk)
  7. Anxiety
  8. Asthenia (weakness)
  9. Cachexia (loss of weight)
  10. Depression

30-39:

  1. Anaemia (lack of blood)
  2. Anxiety
  3. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  4. Dizziness
  5. Dyspnoea (difficult or laboured respiration)
  6. Feeling hot
  7. Haematoma (collection of blood outside the blood vessels)
  8. Haemorrhagic diathesis (bleeding tendency)
  9. Heparin-induced thrombocytopenia
  10. Hypoaesthesia (reduced sense of touch or sensation)

40-49:

  1. Renal failure (kidney dysfunction)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Emotional distress
  5. Pain
  6. Renal impairment (severely reduced kidney function)
  7. Death
  8. Fear
  9. Injury
  10. Multi-organ failure (multisystem organ failure)

50-59:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Vomiting
  3. Abdominal pain
  4. Arrhythmia (irregular heartbeat)
  5. Asthenia (weakness)
  6. Back pain
  7. Cardiac arrest
  8. Chills (felling of cold)
  9. Cough
  10. Decreased appetite

60+:

  1. Hypotension (abnormally low blood pressure)
  2. Anaemia (lack of blood)
  3. Bradycardia (abnormally slow heart action)
  4. Confusional state
  5. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Hyperhidrosis (abnormally increased sweating)
  8. Leukocytosis (increased white blood cells)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

  1. Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 8 people, 14.55%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 14.55%
  3. Pain: 7 people, 12.73%
  4. High Blood Pressure: 7 people, 12.73%
  5. Nephrogenic Anaemia (anaemia due to kidney disease): 6 people, 10.91%
  6. High Blood Cholesterol: 5 people, 9.09%
  7. Anaemia (lack of blood): 5 people, 9.09%
  8. Constipation: 4 people, 7.27%
  9. Indigestion: 3 people, 5.45%
  10. Gastric Ulcer (stomach ulcer): 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cefazolin and Renagel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cefazolin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Renagel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefazolin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Renagel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cefazolin sodium and sevelamer hydrochloride (the active ingredients of Cefazolin and Renagel, respectively), and Cefazolin and Renagel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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