Cefazolin and Xyzal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefazolin (cefazolin sodium) and Xyzal (levocetirizine dihydrochloride). Common drug interactions include staphylococcal infection among females and rash maculo-papular among males.

The phase IV clinical study analyzes what interactions people have when they take Cefazolin and Xyzal. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

What is Xyzal?

Xyzal has active ingredients of levocetirizine dihydrochloride. It is often used in allergies. eHealthMe is studying from 21,479 Xyzal users. Check the latest studies of Xyzal.

On Jul, 12, 2026

44 people who take Cefazolin and Xyzal together, and have interactions are studied.

What are the common drug interactions of Cefazolin and Xyzal, by gender? *:

female:

Staphylococcal infection (an infection with staphylococcus bacteria)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Urinary tract infection
Extrasystoles
Anaemia (lack of blood)
White blood cell count decreased
Pyrexia (fever)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Cardiac failure
Pulmonary arteriovenous fistula

male:

Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Jaw disorder (jaw disease)
Neurosis (a class of functional mental disorders involving distress but neither delusions nor hallucinations)
Paralysis
Speech disorder
Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
Tenderness (pain or discomfort when an affected area is touched)
Trismus (reduced opening of the jaws)
Viith nerve paralysis

What are the common drug interactions of Cefazolin and Xyzal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Extrasystoles
Anaemia (lack of blood)
White blood cell count decreased
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Atelectasis (partial or complete collapse of the lung)
Brain natriuretic peptide increased
Bronchial obstruction (blockage of the breathing passages to the lungs)
Bronchitis bacterial (inflammation of the mucous membrane in the bronchial tubes due to bacterial infection)
Cardiac failure high output
Central venous pressure increased

30-39:

Pulmonary arteriovenous fistula
Thrombocytopenia (decrease of platelets in blood)
Alopecia (absence of hair from areas of the body)
Pyrexia (fever)
Staphylococcal infection (an infection with staphylococcus bacteria)

40-49:

Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Immune system disorder

50-59:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

60+:

Altered state of consciousness (altered state of mind)
Renal failure (kidney dysfunction)
Headache (pain in head)
Hypotonia (low muscle tone)
Jaw disorder (jaw disease)
Neurosis (a class of functional mental disorders involving distress but neither delusions nor hallucinations)
Paralysis
Speech disorder
Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
Tenderness (pain or discomfort when an affected area is touched)

What are the existing conditions these people have? *

Constipation: 10 people, 22.73%
Back Pain: 7 people, 15.91%
Insomnia (sleeplessness): 7 people, 15.91%
Abdominal Pain Upper: 6 people, 13.64%
Gout (uric acid crystals building up in the body): 6 people, 13.64%
Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 6 people, 13.64%
Hyperglycemia (high blood sugar): 6 people, 13.64%
Coughing Up Blood: 6 people, 13.64%
Cough: 6 people, 13.64%
Nausea (feeling of having an urge to vomit): 6 people, 13.64%

* Approximation only. Some reports may have incomplete information.

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