Cefdinir and Advil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefdinir (cefdinir) and Advil (ibuprofen). Common drug interactions include emotional distress among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Cefdinir and Advil. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Cefdinir?

Cefdinir has active ingredients of cefdinir. It is often used in sinusitis. eHealthMe is studying from 9,210 Cefdinir users. Check the latest studies of Cefdinir.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,534 Advil users. Check the latest studies of Advil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 15, 2026

82 people who take Cefdinir and Advil together, and have interactions are studied.

Cefdinir and Advil drug interactions.

What are the common drug interactions of Cefdinir and Advil, by gender? *:

female:

  1. Emotional distress
  2. Gait disturbance
  3. Hyperhidrosis (abnormally increased sweating)
  4. Hypersensitivity
  5. Incontinence (lack of moderation or self-control)
  6. Mania (a state of abnormally elevated or irritable mood)
  7. Memory impairment
  8. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  9. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
  10. Osteopenia (a condition where bone mineral density is lower than normal)

male:

  1. Cellulitis (infection under the skin)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Urethral disorder
  4. White blood cell count decreased
  5. Back disorder
  6. Chest discomfort
  7. Depression
  8. Diarrhoea
  9. Dyspnoea (difficult or laboured respiration)
  10. Epistaxis (bleed from the nose)

What are the common drug interactions of Cefdinir and Advil, by age (0-1 to 60+)? *:

0-1:

  1. Diarrhoea
  2. Epistaxis (bleed from the nose)
  3. Faeces discoloured

2-9:

n/a

10-19:

  1. Abdominal discomfort
  2. Abdominal pain
  3. Arthralgia (joint pain)
  4. Bone abscess
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Nausea (feeling of having an urge to vomit)
  7. Neoplasm (tumour)
  8. Pneumonia
  9. Polycystic ovaries (cysts in the ovaries that occurs when the follicle stops developing)
  10. Postoperative wound infection

20-29:

  1. Chest pain
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Dyspnoea (difficult or laboured respiration)
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Agitation (state of anxiety or nervous excitement)
  6. Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
  7. Burning sensation
  8. Cholecystitis chronic (long lasting infection of gallbladder)
  9. Depression
  10. Diarrhoea

30-39:

  1. Anxiety
  2. Chronic kidney disease
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Depression
  5. Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
  6. Thrombosis (formation of a blood clot inside a blood vessel)

40-49:

  1. Bacterial infection
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  4. Influenza
  5. Infusion site induration
  6. Infusion site pruritus (severe itching at infusion site)
  7. Kidney infection
  8. Upper respiratory tract infection
  9. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  10. Lower respiratory tract infection

50-59:

  1. Depressed mood
  2. Gait disturbance
  3. Incontinence (lack of moderation or self-control)
  4. Mania (a state of abnormally elevated or irritable mood)
  5. Memory impairment
  6. Pain in extremity
  7. Renal failure (kidney dysfunction)
  8. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  9. Sleep disorder
  10. Synovial cyst (cyst of joint filled with synovial fluid)

60+:

  1. Suicidal ideation
  2. Upper respiratory tract infection
  3. Panic attack
  4. Peripheral swelling
  5. Pneumonia
  6. Pneumonia bacterial (pneumonia associated with bacterial infection)
  7. Pruritus (severe itching of the skin)
  8. Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
  9. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  10. Vaginal infection

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 16 people, 19.51%
  2. Depression: 11 people, 13.41%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 9.76%
  4. Multiple Myeloma (cancer of the plasma cells): 8 people, 9.76%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 9.76%
  6. Primary Immunodeficiency Syndrome: 6 people, 7.32%
  7. High Blood Pressure: 6 people, 7.32%
  8. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 5 people, 6.10%

* Approximation only. Some reports may have incomplete information.

Do you take Cefdinir and Advil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cefdinir and Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cefdinir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefdinir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Advil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cefdinir and ibuprofen (the active ingredients of Cefdinir and Advil, respectively), and Cefdinir and Advil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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