Cefixime and Ambien drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cefixime (cefixime) and Ambien (zolpidem tartrate). Common drug interactions include blood pressure increased among females and anhedonia among males.
The phase IV clinical study analyzes what interactions people have when they take Cefixime and Ambien. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.
What is Cefixime?
Cefixime has active ingredients of cefixime. eHealthMe is studying from 3,237 Cefixime users. Check the latest studies of Cefixime.
What is Ambien?
Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.
46 people who take Cefixime and Ambien together, and have interactions are studied.

What are the common drug interactions of Cefixime and Ambien, by gender? *:
female:
- Blood pressure increased
- Intervertebral disc degeneration (spinal disc degeneration)
- Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
- Anxiety
- Blood sodium increased
- Depression
- Emotional distress
- Fatigue (feeling of tiredness)
- Meniere's disease (a disorder of the inner ear that can affect hearing and balance to a varying degree)
- Pain
male:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Vitamin d deficiency
- Blood creatinine increased
- Bone density decreased
- Chronic kidney disease
- Depression
- Emotional distress
- Pain
- Renal failure (kidney dysfunction)
What are the common drug interactions of Cefixime and Ambien, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anxiety
- Arthralgia (joint pain)
- Depression
- Emotional distress
- Fracture
- Fractured sacrum
- Gait disturbance
- Hip fracture
- Joint dislocation (a joint position is changed from normal position)
- Joint injury
40-49:
- Renal impairment (severely reduced kidney function)
- Renal injury (kidney injury)
- Meniere's disease (a disorder of the inner ear that can affect hearing and balance to a varying degree)
- Blood pressure increased
- Blood sodium increased
- Malaise (a feeling of general discomfort or uneasiness)
- Vitamin b12 deficiency
- Blood pressure decreased
- Gait disturbance
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
50-59:
- Fatigue (feeling of tiredness)
- Heart rate increased
- Hypersensitivity
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Oedema peripheral (superficial swelling)
- Peripheral swelling
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Cataract (clouding of the lens inside the eye)
60+:
- Fatigue (feeling of tiredness)
- Muscle spasms (muscle contraction)
- Skin atrophy (wasting of skin)
- Stomatitis (inflammation of mucous membrane of mouth)
- Acantholysis (progressive movement disorder)
- Anaemia of chronic disease
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arthralgia (joint pain)
- Blood pressure increased
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 28.26%
- Sleep Disorder: 12 people, 26.09%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 21.74%
- Hiv Infection: 6 people, 13.04%
- Drowsiness: 5 people, 10.87%
- Stress And Anxiety: 3 people, 6.52%
- Gastric Ulcer (stomach ulcer): 3 people, 6.52%
- Blood Pressure Abnormal: 3 people, 6.52%
- Cardiac Disorder: 3 people, 6.52%
- Depression: 3 people, 6.52%
* Approximation only. Some reports may have incomplete information.
Do you take Cefixime and Ambien?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cefixime and Ambien:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cefixime:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ambien:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cefixime and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ambien and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cefixime and zolpidem tartrate (the active ingredients of Cefixime and Ambien, respectively), and Cefixime and Ambien (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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