Cefixime and Cefazolin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefixime (cefixime) and Cefazolin (cefazolin sodium). Common drug interactions include foetal exposure during pregnancy among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Cefixime and Cefazolin. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Cefixime?

Cefixime has active ingredients of cefixime. eHealthMe is studying from 3,237 Cefixime users. Check the latest studies of Cefixime.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

41 people who take Cefixime and Cefazolin together, and have interactions are studied.

Cefixime and Cefazolin drug interactions.

What are the common drug interactions of Cefixime and Cefazolin, by gender? *:

female:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy)
Premature baby
Oligohydramnios (a condition in pregnancy characterized by a deficiency of amniotic fluid)
Dehydration (dryness resulting from the removal of water)
Maternal exposure during pregnancy (use of substance during pregnancy)
Urinary tract infection
Vomiting
Angioedema (rapid swelling of the dermis)
Apgar score low

male:

Abdominal pain upper
Blood pressure decreased
Hot flush (sudden feelings of heat)
Nasopharyngitis (inflammation of the nasopharynx)
Pain
Pallor
Presyncope
Rhinorrhoea (watery mucus discharge from the nose)
Slow response to stimuli (slow response by nerves)
Throat irritation

What are the common drug interactions of Cefixime and Cefazolin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Dehydration (dryness resulting from the removal of water)
Urinary tract infection
Vomiting

10-19:

Wound dehiscence (a surgical incision reopens either internally or externally)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Impaired healing

20-29:

Abdominal pain upper
Blood pressure decreased
Chills (felling of cold)
Cough
Decreased appetite
Discomfort
Gastrointestinal inflammation (inflammation of stomach and intestine)
Haemorrhage (bleeding)
Heart rate increased
Heart rate irregular

30-39:

Maternal exposure during pregnancy (use of substance during pregnancy)
Oligohydramnios (a condition in pregnancy characterized by a deficiency of amniotic fluid)
Premature delivery
Anxiety
Arthralgia (joint pain)
Depression
Emotional distress
Fracture
Fractured sacrum
Gait disturbance

40-49:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Delirium (wild excitement)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Abnormal behaviour
B precursor type acute leukaemia (lymphoid cancer)

50-59:

Angioedema (rapid swelling of the dermis)
Erythema (redness of the skin)
Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)

60+:

Clostridium test positive
Neutropenia (an abnormally low number of neutrophils)
Plasma cell myeloma (cancer that begins in plasma cells)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 11 people, 26.83%
Hepatoblastoma (liver cancer): 4 people, 9.76%
Allergies: 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Cefixime and Cefazolin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously