Cefixime and Imodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefixime (cefixime) and Imodium (loperamide hydrochloride). Common drug interactions include sinusitis among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Cefixime and Imodium. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Cefixime?

Cefixime has active ingredients of cefixime. eHealthMe is studying from 3,237 Cefixime users. Check the latest studies of Cefixime.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.



On Jul, 08, 2026

24 people who take Cefixime and Imodium together, and have interactions are studied.

Cefixime and Imodium drug interactions.

What are the common drug interactions of Cefixime and Imodium, by gender? *:

female:

  1. Sinusitis (inflammation of sinus)
  2. Ulcer
  3. Drug ineffective
  4. Nausea (feeling of having an urge to vomit)
  5. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  6. Dyspepsia (indigestion)
  7. Infusion related reaction
  8. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Pain

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Vomiting
  3. Gastritis (inflammation of stomach)
  4. Ileus (a painful obstruction of the ileum or other part of the intestine)
  5. Mouth ulceration (mouth ulcers)
  6. Overdose
  7. Rash macular (small, flat red spots)
  8. Abdominal discomfort
  9. Back pain
  10. Blood pressure increased

What are the common drug interactions of Cefixime and Imodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal discomfort
  2. Cardiac arrest
  3. Gastritis (inflammation of stomach)
  4. Nausea (feeling of having an urge to vomit)
  5. Overdose
  6. Vomiting

50-59:

  1. Arthralgia (joint pain)
  2. Balance disorder
  3. Dyspnoea (difficult or laboured respiration)
  4. Headache (pain in head)
  5. Asthenia (weakness)
  6. Back pain
  7. Bone pain
  8. Decreased appetite
  9. Dehydration (dryness resulting from the removal of water)
  10. Disturbance in attention

60+:

  1. Drug ineffective
  2. Nausea (feeling of having an urge to vomit)
  3. Pyrexia (fever)
  4. Weight decreased
  5. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  6. Back pain
  7. Blood pressure increased
  8. Decreased appetite
  9. Dehydration (dryness resulting from the removal of water)
  10. Dry skin

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 20.83%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 20.83%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 16.67%
  4. Hypokalemia (low potassium): 3 people, 12.50%
  5. Hypersensitivity: 3 people, 12.50%
  6. High Blood Pressure: 3 people, 12.50%
  7. Allergies: 3 people, 12.50%
  8. Urinary Tract Infection: 2 people, 8.33%
  9. Renal Cell Carcinoma (a kidney cancer): 2 people, 8.33%
  10. Pain: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Cefixime and Imodium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cefixime and Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cefixime:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefixime and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cefixime and loperamide hydrochloride (the active ingredients of Cefixime and Imodium, respectively), and Cefixime and Imodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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