Cefpodoxime proxetil and Rocephin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefpodoxime proxetil (cefpodoxime proxetil) and Rocephin (ceftriaxone sodium). Common drug interactions include pyelonephritis acute among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Cefpodoxime proxetil and Rocephin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Cefpodoxime proxetil?

Cefpodoxime proxetil has active ingredients of cefpodoxime proxetil. eHealthMe is studying from 1,357 Cefpodoxime proxetil users. Check the latest studies of Cefpodoxime proxetil.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.



On Jul, 27, 2026

14 people who take Cefpodoxime proxetil and Rocephin together, and have interactions are studied.

Cefpodoxime proxetil and Rocephin drug interactions.

What are the common drug interactions of Cefpodoxime Proxetil and Rocephin, by gender? *:

female:

  1. Pyelonephritis acute (sudden inflammation of kidney caused by bacteria)
  2. Death
  3. Chronic kidney disease
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Pregnancy with contraceptive device
  6. Renal failure (kidney dysfunction)
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Activated partial thromboplastin time prolonged
  9. Allergic granulomatous angiitis (allergic inflammation of a blood vessel or lymph duct)
  10. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)

male:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Leukopenia (less number of white blood cells in blood)
  4. Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
  5. Pyrexia (fever)
  6. Thrombocytopenia (decrease of platelets in blood)

What are the common drug interactions of Cefpodoxime Proxetil and Rocephin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Abdominal pain
  2. Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
  3. Pyrexia (fever)

10-19:

n/a

20-29:

n/a

30-39:

  1. Escherichia infection (bacterial infection by escherichia coli)
  2. Lupus nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue)
  3. Nephrolithiasis (calculi in the kidneys)
  4. Pyelonephritis acute (sudden inflammation of kidney caused by bacteria)
  5. Pregnancy with contraceptive device

40-49:

  1. Allergic granulomatous angiitis (allergic inflammation of a blood vessel or lymph duct)
  2. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  3. Antimitochondrial antibody positive
  4. Antineutrophil cytoplasmic antibody positive
  5. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
  6. Bundle branch block (disruption in the normal flow of electrical pulses that drive the heart beat)
  7. Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
  8. Candidiasis (candidiasis or thrush is a fungal infection)
  9. Cardiac failure
  10. Cardiomegaly (increased size of heart than normal)

50-59:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

  1. Acute generalised exanthematous pustulosis (acute febrile drug eruption)
  2. Death
  3. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  4. Emotional disorder
  5. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  6. Haematocrit decreased
  7. Haematoma (collection of blood outside the blood vessels)
  8. Haemoglobin decreased
  9. Haemorrhage subcutaneous (bleeding from skin)
  10. Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

  1. Kidney Infection (Pyelonephritis): 3 people, 21.43%
  2. Pneumonia: 3 people, 21.43%
  3. The Flu (the flu is caused by an influenza virus): 2 people, 14.29%
  4. Blood Pressure Abnormal: 2 people, 14.29%
  5. Diabetes: 2 people, 14.29%
  6. Nasopharyngitis (inflammation of the nasopharynx): 2 people, 14.29%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
  8. High Blood Cholesterol: 2 people, 14.29%
  9. Hypersensitivity: 2 people, 14.29%
  10. Birth Control: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Cefpodoxime proxetil and Rocephin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cefpodoxime proxetil and Rocephin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cefpodoxime proxetil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rocephin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefpodoxime proxetil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rocephin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cefpodoxime proxetil and ceftriaxone sodium (the active ingredients of Cefpodoxime proxetil and Rocephin, respectively), and Cefpodoxime proxetil and Rocephin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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