Cefpodoxime proxetil and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefpodoxime proxetil (cefpodoxime proxetil) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include nausea among females and actinic keratosis among males.

The phase IV clinical study analyzes what interactions people have when they take Cefpodoxime proxetil and Valacyclovir. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Cefpodoxime proxetil?

Cefpodoxime proxetil has active ingredients of cefpodoxime proxetil. eHealthMe is studying from 1,357 Cefpodoxime proxetil users. Check the latest studies of Cefpodoxime proxetil.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

On Jul, 15, 2026

39 people who take Cefpodoxime proxetil and Valacyclovir together, and have interactions are studied.

Cefpodoxime proxetil and Valacyclovir drug interactions.

What are the common drug interactions of Cefpodoxime Proxetil and Valacyclovir, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Peripheral swelling
Platelet count decreased
Polyarthritis (arthritis which involves 5 or more joints simultaneously)
Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)
Pulmonary alveolar haemorrhage (acute bleeding)
Renal failure acute (rapid kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)
Small intestinal obstruction (blockage in small intestine)

male:

Actinic keratosis (skin disease due to sun exposure)
Photosensitivity reaction
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthralgia (joint pain)
Asthenia (weakness)
Atypical mycobacterium test positive
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Blood creatinine increased
Bone density decreased
Bone loss

What are the common drug interactions of Cefpodoxime Proxetil and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Atypical mycobacterium test positive
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Disseminated cryptococcosis (one of the acquired immune deficiency syndrome defining criteria and the most common cause of life threatening meningitis)
Hepatotoxicity (chemical-driven liver damage)
Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)

40-49:

n/a

50-59:

Alanine aminotransferase increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac failure congestive
Pneumonia
Abdominal pain
Anxiety
Arthralgia (joint pain)
Blood creatinine increased
Bone density decreased
Bone loss

60+:

Disease progression
Mucosal inflammation (infection of mucous membrane)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Agitation (state of anxiety or nervous excitement)
Anxiety
Asthenia (weakness)
Cardiac arrest
Chest discomfort
Chronic kidney disease
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 17.95%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 15.38%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 10.26%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 10.26%
Adverse Event: 4 people, 10.26%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 3 people, 7.69%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 7.69%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.13%
High Blood Pressure: 2 people, 5.13%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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