Ceftin and Enbrel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ceftin (cefuroxime axetil) and Enbrel (etanercept). Common drug interactions include otitis externa among females and ear infection among males.
The phase IV clinical study analyzes what interactions people have when they take Ceftin and Enbrel. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.
What is Ceftin?
Ceftin has active ingredients of cefuroxime axetil. It is often used in sinusitis. eHealthMe is studying from 4,333 Ceftin users. Check the latest studies of Ceftin.
What is Enbrel?
Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.
70 people who take Ceftin and Enbrel together, and have interactions are studied.

What are the common drug interactions of Ceftin and Enbrel, by gender? *:
female:
- Otitis externa (external ear infection)
- Cor pulmonale chronic (long lasting enlargement of the right ventricle of the heart)
- Gastroduodenitis (an inflammation of the mucous membrane of the stomach and duodenum)
- Uterine enlargement
- Cardiac failure congestive
- Pain
- Diarrhoea
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Swelling
male:
- Ear infection
- Psoriasis (immune-mediated disease that affects the skin)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Tonsillitis bacterial (bacterial infection of tonsil)
- Anaemia (lack of blood)
- B-cell lymphoma (blood cancer affecting b cells)
- Chronic tonsillitis (long lasting inflammation of tonsil)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Hypotension (abnormally low blood pressure)
What are the common drug interactions of Ceftin and Enbrel, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal discomfort
- Abdominal pain
- Abdominal pain upper
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholesterosis (abnormal deposition of cholesterol in tissues)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Diarrhoea
- Faeces discoloured
- Hypokalaemia (low potassium)
30-39:
- Pustular psoriasis (raised bumps on the skin that are filled with pus)
40-49:
- Convulsion neonatal (muscle contraction and relaxation rapidly in neonate)
- Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
- Retinal haemorrhage (bleeding from retina)
- Sepsis neonatal (a bacterial infection in the blood. it is found in infants during the first month of life)
- Talipes
- Transverse sinus thrombosis (a blood clot in transverse sinus)
- Vitreous haemorrhage (intraocular (inside the eye) bleeding)
- Anaphylactic reaction (serious allergic reaction)
- Injection site erythema (redness at injection site)
- Injection site pain
50-59:
- Device failure
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Scab (a hard coating on the skin formed during the wound healing)
- Tooth extraction
- Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
- Osteonecrosis of jaw (death of bone of jaw)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Hyperglycaemia (high blood sugar)
- Foot deformity (functional disability of foot)
- Otitis externa (external ear infection)
60+:
- Pain
- Rash
- Depression
- Drug effect decreased
- Fatigue (feeling of tiredness)
- Gastrointestinal pain
- Headache (pain in head)
- Idiopathic pulmonary fibrosis (chronic lung disease)
- Injection site mass
- Muscle spasms (muscle contraction)
What are the existing conditions these people have? *
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 28 people, 40.00%
- Osteoporosis (bones weak and more likely to break): 28 people, 40.00%
- Thrombocytopenia (decrease of platelets in blood): 11 people, 15.71%
- Psoriasis (immune-mediated disease that affects the skin): 4 people, 5.71%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 5.71%
- Chest Pain: 4 people, 5.71%
* Approximation only. Some reports may have incomplete information.
Do you take Ceftin and Enbrel?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ceftin and Enbrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ceftin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Enbrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ceftin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Enbrel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Sahoo HB, Rath B, Behera JP, Moharana CS, "Cefuroxime axetil associated oral eruption: A case report", Apollo Medicine, 2016 Jun .
- Sahoo HB, Rath B, Behera JP, Moharana CS, "Cefuroxime axetil associated oral eruption: A case report", Apollo Medicine, 2016 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on cefuroxime axetil and etanercept (the active ingredients of Ceftin and Enbrel, respectively), and Ceftin and Enbrel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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