Ceftin and Floxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ceftin (cefuroxime axetil) and Floxin (ofloxacin). Common drug interactions include confusion among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Ceftin and Floxin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Ceftin?

Ceftin has active ingredients of cefuroxime axetil. It is often used in sinusitis. eHealthMe is studying from 4,333 Ceftin users. Check the latest studies of Ceftin.

What is Floxin?

Floxin has active ingredients of ofloxacin. eHealthMe is studying from 1,737 Floxin users. Check the latest studies of Floxin.



On Jul, 12, 2026

16 people who take Ceftin and Floxin together, and have interactions are studied.

Ceftin and Floxin drug interactions.

What are the common drug interactions of Ceftin and Floxin, by gender? *:

female:

  1. Confusion
  2. Cough
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  5. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  6. Dizziness
  7. Drug toxicity
  8. Dysmenorrhoea (painful menstruation)
  9. Dyspnoea (difficult or laboured respiration)
  10. Eye disorder

male:

  1. Pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Hyperhidrosis (abnormally increased sweating)
  4. Hypokalaemia (low potassium)
  5. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  6. Occult blood positive
  7. Palpitations (feelings or sensations that your heart is pounding or racing)
  8. Pneumonia
  9. Renal failure acute (rapid kidney dysfunction)
  10. Syncope (loss of consciousness with an inability to maintain postural tone)

What are the common drug interactions of Ceftin and Floxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  2. Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)
  3. Dysmenorrhoea (painful menstruation)
  4. Pregnancy

20-29:

  1. Pain

30-39:

  1. Pneumonia
  2. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  3. Anaemia (lack of blood)
  4. Asthma
  5. Blood alkaline phosphatase increased
  6. Blood bilirubin increased
  7. Blood lactate dehydrogenase increased
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Chronic obstructive airways disease
  10. Gamma-glutamyltransferase increased

40-49:

n/a

50-59:

n/a

60+:

  1. Cardiac failure congestive
  2. Cardiomegaly (increased size of heart than normal)
  3. Emotional distress
  4. Hyperhidrosis (abnormally increased sweating)
  5. Hypokalaemia (low potassium)
  6. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  7. Occult blood positive
  8. Pain
  9. Palpitations (feelings or sensations that your heart is pounding or racing)
  10. Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 25.00%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
  3. Pneumonia Aspergillus (invasive type is a serious infection with pneumonia that can spread to other parts of the body): 1 person, 6.25%
  4. Pain: 1 person, 6.25%
  5. Oedema Peripheral (superficial swelling): 1 person, 6.25%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Ceftin and Floxin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ceftin and Floxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ceftin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Floxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ceftin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Floxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cefuroxime axetil and ofloxacin (the active ingredients of Ceftin and Floxin, respectively), and Ceftin and Floxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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