Ceftriaxone sodium and Acyclovir sodium drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ceftriaxone sodium (ceftriaxone sodium) and Acyclovir sodium (acyclovir sodium). Common drug interactions include blood creatinine increased among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Ceftriaxone sodium and Acyclovir sodium. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Ceftriaxone sodium?
Ceftriaxone sodium has active ingredients of ceftriaxone sodium. eHealthMe is studying from 6,549 Ceftriaxone sodium users. Check the latest studies of Ceftriaxone sodium.
What is Acyclovir sodium?
Acyclovir sodium has active ingredients of acyclovir sodium. eHealthMe is studying from 1,813 Acyclovir sodium users. Check the latest studies of Acyclovir sodium.
15 people who take Ceftriaxone sodium and Acyclovir sodium together, and have interactions are studied.

What are the common drug interactions of Ceftriaxone Sodium and Acyclovir Sodium, by gender? *:
female:
- Blood creatinine increased
- Drug ineffective
- Anaemia (lack of blood)
- Circulatory collapse
- Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus)
- Haemorrhage (bleeding)
- Histiocytosis haematophagic
- Hyperammonaemia
- Hyperuricaemia (level of uric acid in the blood that is abnormally high)
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
male:
- Drug ineffective
- Blood creatinine increased
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
- Nuclear magnetic resonance imaging brain
- Pain in extremity
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
- Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
- Quadriparesis (muscle weakness affecting all four limbs)
- Spastic paraplegia (impairment in motor or sensory function of the lower extremities)
What are the common drug interactions of Ceftriaxone Sodium and Acyclovir Sodium, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Anaemia (lack of blood)
- Circulatory collapse
- Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus)
- Haemorrhage (bleeding)
- Histiocytosis haematophagic
- Hyperammonaemia
- Hyperuricaemia (level of uric acid in the blood that is abnormally high)
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
- Infection
- Oedema (fluid collection in tissue)
10-19:
- Blood creatinine increased
- Blood pressure increased
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
- Vision blurred
- Vomiting
20-29:
- Blood creatinine increased
- Agitation (state of anxiety or nervous excitement)
- Drug hypersensitivity
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Hypotension (abnormally low blood pressure)
- Rash
30-39:
- Drug ineffective
- Multiple-drug resistance
40-49:
- Drug ineffective
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
- Quadriparesis (muscle weakness affecting all four limbs)
50-59:
- Drug ineffective
60+:
- Disease progression
- Encephalitis viral (inflammation of the brain due to viral infection)
- Hypoaesthesia (reduced sense of touch or sensation)
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Myelitis (infection or the inflammation of white matter or gray matter of spinal cord which is a part of central nervous system)
- Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
- Nuclear magnetic resonance imaging brain
- Pain in extremity
- Spastic paraplegia (impairment in motor or sensory function of the lower extremities)
- Splenomegaly (enlargement of spleen)
What are the existing conditions these people have? *
- Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 5 people, 33.33%
- General Anaesthesia: 4 people, 26.67%
- Encephalitis (inflammation of the brain): 3 people, 20.00%
- Neck Pain: 2 people, 13.33%
- Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 2 people, 13.33%
- Headache (pain in head): 2 people, 13.33%
- Fever: 2 people, 13.33%
- Urinary Tract Infection: 1 person, 6.67%
- Relapsing Fever (bacterial infection characterized by recurring episodes of fever, headache, muscle and joint aches, and nausea): 1 person, 6.67%
- Pain: 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Ceftriaxone sodium and Acyclovir sodium?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Ceftriaxone sodium (6,549 reports)
- Acyclovir sodium (1,813 reports)
Browse all drug interactions of Ceftriaxone sodium and Acyclovir sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ceftriaxone sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Acyclovir sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ceftriaxone sodium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acyclovir sodium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on ceftriaxone sodium and acyclovir sodium (the active ingredients of Ceftriaxone sodium and Acyclovir sodium, respectively), and Ceftriaxone sodium and Acyclovir sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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