Ceftriaxone sodium and Duphalac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ceftriaxone sodium (ceftriaxone sodium) and Duphalac (lactulose). Common drug interactions include diarrhoea among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Ceftriaxone sodium and Duphalac. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Ceftriaxone sodium?

Ceftriaxone sodium has active ingredients of ceftriaxone sodium. eHealthMe is studying from 6,549 Ceftriaxone sodium users. Check the latest studies of Ceftriaxone sodium.

What is Duphalac?

Duphalac has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 5,152 Duphalac users. Check the latest studies of Duphalac.



On Jul, 08, 2026

14 people who take Ceftriaxone sodium and Duphalac together, and have interactions are studied.

Ceftriaxone sodium and Duphalac drug interactions.

What are the common drug interactions of Ceftriaxone Sodium and Duphalac, by gender? *:

female:

  1. Diarrhoea
  2. Dyspepsia (indigestion)
  3. Electrocardiogram qt prolonged
  4. Febrile neutropenia (fever with reduced white blood cells)
  5. Headache (pain in head)
  6. Neck pain
  7. Oral candidiasis (fungal infection of mouth)
  8. Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
  9. Adverse event
  10. Decreased appetite

male:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Decreased appetite
  3. Nausea (feeling of having an urge to vomit)
  4. Confusional state
  5. International normalised ratio increased
  6. Rash papular (redness with papule)
  7. Rectal haemorrhage (bleeding from anus)
  8. Renal failure (kidney dysfunction)

What are the common drug interactions of Ceftriaxone Sodium and Duphalac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Decreased appetite
  2. Nausea (feeling of having an urge to vomit)

20-29:

n/a

30-39:

  1. Decreased appetite
  2. Nausea (feeling of having an urge to vomit)
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Stomatitis (inflammation of mucous membrane of mouth)

40-49:

n/a

50-59:

  1. Electrocardiogram qt prolonged
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Headache (pain in head)
  4. Neck pain
  5. Oral candidiasis (fungal infection of mouth)
  6. Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
  7. Escherichia sepsis (bacterial infection by escherichia coli)
  8. Neutropenia (an abnormally low number of neutrophils)
  9. C-reactive protein increased
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

60+:

  1. Confusional state
  2. International normalised ratio increased
  3. Rash papular (redness with papule)
  4. Rectal haemorrhage (bleeding from anus)
  5. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Allergies: 3 people, 21.43%
  2. Enlarged Prostate: 3 people, 21.43%
  3. Urination - Painful: 2 people, 14.29%
  4. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 14.29%
  5. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 14.29%
  6. Cancer Pain: 2 people, 14.29%
  7. Depression: 2 people, 14.29%
  8. General Anaesthesia: 2 people, 14.29%
  9. Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 2 people, 14.29%
  10. Hypotension (abnormally low blood pressure): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ceftriaxone sodium and Duphalac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ceftriaxone sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Duphalac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ceftriaxone sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Duphalac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ceftriaxone sodium and lactulose (the active ingredients of Ceftriaxone sodium and Duphalac, respectively), and Ceftriaxone sodium and Duphalac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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