Cefuroxime and Fentanyl citrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefuroxime (cefuroxime sodium) and Fentanyl citrate (fentanyl citrate). Common drug interactions include thrombocytopenia among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Cefuroxime and Fentanyl citrate. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Cefuroxime?

Cefuroxime has active ingredients of cefuroxime sodium. It is often used in sinusitis. eHealthMe is studying from 12,999 Cefuroxime users. Check the latest studies of Cefuroxime.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

On Jul, 16, 2026

71 people who take Cefuroxime and Fentanyl citrate together, and have interactions are studied.

Cefuroxime and Fentanyl citrate drug interactions.

What are the common drug interactions of Cefuroxime and Fentanyl Citrate, by gender? *:

female:

Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Visual impairment
Cardiac arrest
Drug hypersensitivity
Hypotension (abnormally low blood pressure)
Injury
Pulmonary embolism (blockage of the main artery of the lung)
Aphasia (damage to the parts of the brain that control language)

male:

Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Hypertension (high blood pressure)
Renal failure (kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Pyrexia (fever)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
General physical health deterioration (weak health status)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

What are the common drug interactions of Cefuroxime and Fentanyl Citrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Brain injury
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cerebral palsy
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Choking sensation (feeling of obstruction in respiratory system)
Circulatory collapse
Dehydration (dryness resulting from the removal of water)
Developmental delay

10-19:

Drug ineffective
Nausea (feeling of having an urge to vomit)
Cardiogenic shock (inadequate circulation of blood)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Dizziness
Drug intolerance (drug sensitivity)
Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Gastrointestinal necrosis (destruction of gastrointestinal organ)
Genital pain (pain in genital)
Hepatic failure (liver failure)

20-29:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Cardiac arrest
Coma (state of unconsciousness lasting more than six hours)

30-39:

Haemophilic arthropathy (permanent joint disease)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Cardiac arrest
Hypoventilation (too shallow or too slow breathing, which does not meet the needs of the body)
Laryngeal oedema (swelling of larynx)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Oxygen saturation decreased

40-49:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Injury
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Pulmonary embolism (blockage of the main artery of the lung)

50-59:

Ascites (accumulation of fluid in the abdominal cavity)
Coagulopathy (blood's ability to clot is impaired)
Dizziness
Dysuria (painful or difficult urination)
Hepatic failure (liver failure)
Insomnia (sleeplessness)
Liver carcinoma ruptured (ruptured liver cancer tumour)
Oedema (fluid collection in tissue)
Weight decreased
Drug hypersensitivity

60+:

Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
General physical health deterioration (weak health status)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)

What are the existing conditions these people have? *

Sedation: 7 people, 9.86%
Local Anaesthesia: 7 people, 9.86%
Nausea (feeling of having an urge to vomit): 6 people, 8.45%
Constipation: 6 people, 8.45%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 5.63%
High Blood Pressure: 4 people, 5.63%
Cough: 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

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