Cefuroxime and Isosorbide dinitrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefuroxime (cefuroxime sodium) and Isosorbide dinitrate (isosorbide dinitrate). Common drug interactions include electrocardiogram qt prolonged among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Cefuroxime and Isosorbide dinitrate. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Cefuroxime?

Cefuroxime has active ingredients of cefuroxime sodium. It is often used in sinusitis. eHealthMe is studying from 12,999 Cefuroxime users. Check the latest studies of Cefuroxime.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.



On Jul, 16, 2026

30 people who take Cefuroxime and Isosorbide dinitrate together, and have interactions are studied.

Cefuroxime and Isosorbide dinitrate drug interactions.

What are the common drug interactions of Cefuroxime and Isosorbide Dinitrate, by gender? *:

female:

  1. Electrocardiogram qt prolonged
  2. Emotional distress
  3. Fear
  4. Multi-organ failure (multisystem organ failure)
  5. Nervousness
  6. Pain
  7. Renal injury (kidney injury)
  8. Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
  9. Cerebral atrophy (decrement in size of brain)
  10. Intention tremor (brain tremor)

male:

  1. Renal failure (kidney dysfunction)
  2. Cardiac failure congestive
  3. Pain
  4. Renal impairment (severely reduced kidney function)
  5. Renal injury (kidney injury)
  6. Respiratory distress (difficulty in breathing)
  7. Stress
  8. Activated partial thromboplastin time prolonged
  9. Acute respiratory distress syndrome
  10. Alanine aminotransferase increased

What are the common drug interactions of Cefuroxime and Isosorbide Dinitrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Pulmonary sepsis (pus in lungs)
  2. Staphylococcal infection (an infection with staphylococcus bacteria)
  3. Atrioventricular block complete (heart block complete)
  4. Atrioventricular block second degree (heart block second degree)
  5. Bradycardia (abnormally slow heart action)
  6. Cardiac failure congestive
  7. Cardiogenic shock (inadequate circulation of blood)
  8. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  9. Dizziness
  10. Gangrene (body tissue dies)

60+:

  1. Renal failure (kidney dysfunction)
  2. Dyspnoea (difficult or laboured respiration)
  3. Emotional distress
  4. Fear
  5. Hypotension (abnormally low blood pressure)
  6. Pain
  7. Renal injury (kidney injury)
  8. Respiratory distress (difficulty in breathing)
  9. Stress
  10. Asthenia (weakness)

What are the existing conditions these people have? *

  1. High Blood Pressure: 3 people, 10.00%
  2. Nausea (feeling of having an urge to vomit): 3 people, 10.00%
  3. Heart Disease: 2 people, 6.67%
  4. Arrhythmias (irregular heartbeat): 2 people, 6.67%
  5. Bleeding Disorders: 2 people, 6.67%
  6. Blood Calcium Decreased: 2 people, 6.67%
  7. Blood Glucose Increased: 2 people, 6.67%
  8. Blood Potassium Decreased: 2 people, 6.67%
  9. Cardiac Failure: 2 people, 6.67%
  10. Cardiac Failure Congestive: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Cefuroxime and Isosorbide dinitrate?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cefuroxime and Isosorbide dinitrate:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cefuroxime:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Isosorbide dinitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefuroxime and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isosorbide dinitrate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cefuroxime sodium and isosorbide dinitrate (the active ingredients of Cefuroxime and Isosorbide dinitrate, respectively), and Cefuroxime and Isosorbide dinitrate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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