Cefuroxime and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefuroxime (cefuroxime sodium) and Keppra (levetiracetam). Common drug interactions include respiratory syncytial virus bronchiolitis among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Cefuroxime and Keppra. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Cefuroxime?

Cefuroxime has active ingredients of cefuroxime sodium. It is often used in sinusitis. eHealthMe is studying from 12,999 Cefuroxime users. Check the latest studies of Cefuroxime.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

47 people who take Cefuroxime and Keppra together, and have interactions are studied.

Cefuroxime and Keppra drug interactions.

What are the common drug interactions of Cefuroxime and Keppra, by gender? *:

female:

Respiratory syncytial virus bronchiolitis (a lower respiratory tract infection due to virus)
Swelling face
Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
Burning sensation
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Extravasation (leakage of a fluid)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

Anaemia (lack of blood)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Subdural haematoma (blood collects between the skull and the surface of the brain)
Thrombocytopenia (decrease of platelets in blood)
Vomiting

What are the common drug interactions of Cefuroxime and Keppra, by age (0-1 to 60+)? *:

0-1:

Bradycardia neonatal (sinus rhythm with a heart rate below the normal limit in newborn)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Low set ears (depressed positioning of the pinna (outer ear ))
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Neonatal respiratory distress syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)
Premature baby
Retrognathia (a condition in which either or both jaws recede with respect to the frontal plane of the forehead)
Small for dates baby (an unborn baby is growing more slowly and is smaller than most babies are at the same age)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Coma blister

2-9:

n/a

10-19:

Pulmonary embolism (blockage of the main artery of the lung)
Injury
Pain
Pyrexia (fever)

20-29:

Premature delivery
Talipes
Vitamin b12 deficiency
Vitamin b6 deficiency
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Maternal exposure during pregnancy (use of substance during pregnancy)
Pregnancy

30-39:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Injury

40-49:

Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Hypovolaemia (a decreased volume of circulating blood in the body)
Injury
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Pain
Polyuria (production of too much dilute urine)

50-59:

Asthenia (weakness)
Balance disorder
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Diplopia (double vision)
Dysarthria (speech disorder)
Facial bones fracture (bone fracture of face)
Fall
Fatigue (feeling of tiredness)

60+:

Anaemia (lack of blood)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Subdural haematoma (blood collects between the skull and the surface of the brain)
Thrombocytopenia (decrease of platelets in blood)
Vomiting

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 14.89%
Constipation: 7 people, 14.89%
Pain: 7 people, 14.89%
Diabetes: 6 people, 12.77%
Infection: 6 people, 12.77%
Blood Glucose Abnormal: 5 people, 10.64%
Insomnia (sleeplessness): 5 people, 10.64%
Hypersensitivity: 5 people, 10.64%
Depression: 5 people, 10.64%
Nausea (feeling of having an urge to vomit): 4 people, 8.51%

* Approximation only. Some reports may have incomplete information.

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