Cefuroxime and Vancomycin hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cefuroxime (cefuroxime sodium) and Vancomycin hydrochloride (vancomycin hydrochloride). Common drug interactions include drug hypersensitivity among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Cefuroxime and Vancomycin hydrochloride. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Cefuroxime?

Cefuroxime has active ingredients of cefuroxime sodium. It is often used in sinusitis. eHealthMe is studying from 12,999 Cefuroxime users. Check the latest studies of Cefuroxime.

What is Vancomycin hydrochloride?

Vancomycin hydrochloride has active ingredients of vancomycin hydrochloride. It is often used in mrsa infection. eHealthMe is studying from 8,399 Vancomycin hydrochloride users. Check the latest studies of Vancomycin hydrochloride.

On Jul, 31, 2026

32 people who take Cefuroxime and Vancomycin hydrochloride together, and have interactions are studied.

Cefuroxime and Vancomycin hydrochloride drug interactions.

What are the common drug interactions of Cefuroxime and Vancomycin Hydrochloride, by gender? *:

female:

Drug hypersensitivity
Headache (pain in head)
Peripheral swelling
Rash
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Swelling face
Chronic kidney disease
Diarrhoea
Ischaemic cerebral infarction (ischemic stroke resulting from a disturbance in the blood vessels supplying blood to the brain)
Joint warmth

male:

Pyrexia (fever)
Breath sounds
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Pancreatitis (inflammation of pancreas)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Drug level decreased
Gamma-glutamyltransferase increased

What are the common drug interactions of Cefuroxime and Vancomycin Hydrochloride, by age (0-1 to 60+)? *:

0-1:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Drug level decreased
Gamma-glutamyltransferase increased

2-9:

Electrocardiogram qt prolonged
Oedema peripheral (superficial swelling)
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting

10-19:

n/a

20-29:

Acute respiratory failure
Cytomegalovirus gastrointestinal infection (virus infection of stomach and intestine)
Renal impairment (severely reduced kidney function)
Aphasia (damage to the parts of the brain that control language)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug toxicity
Dysarthria (speech disorder)
Dyskinesia (abnormality or impairment of voluntary movement)

30-39:

Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)

40-49:

Breath sounds
Cerebral haemorrhage (bleeding within the brain)
Confusional state
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypotension (abnormally low blood pressure)
Nystagmus (a condition of involuntary eye movement)
Productive cough
Pyrexia (fever)
Coma (state of unconsciousness lasting more than six hours)
Quadriplegia (a four limb paralysis)

50-59:

Arrhythmia (irregular heartbeat)
Brain stem infarction (brainstem stroke)
Chronic kidney disease
Cough
Depression
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Mood disorder due to a general medical condition
Pleural effusion (water on the lungs)
Renal injury (kidney injury)

60+:

Drug hypersensitivity
Headache (pain in head)
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Diarrhoea
Ischaemic cerebral infarction (ischemic stroke resulting from a disturbance in the blood vessels supplying blood to the brain)
Joint warmth
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Sinus pain
Vomiting

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 21.88%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 4 people, 12.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 12.50%
Urinary Tract Infection: 3 people, 9.38%
Infection: 3 people, 9.38%
Asthma: 3 people, 9.38%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 3 people, 9.38%
Cerebral Hypoperfusion (a condition in which the brain doesn't get enough blood): 3 people, 9.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.38%
Acidosis (build-up of carbon dioxide in the blood): 3 people, 9.38%

* Approximation only. Some reports may have incomplete information.

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