Centrum and Alrex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Alrex (loteprednol etabonate). Common drug interactions include intestinal perforation among females and ankle fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Alrex. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Alrex?

Alrex has active ingredients of loteprednol etabonate. eHealthMe is studying from 663 Alrex users. Check the latest studies of Alrex.

On Jul, 09, 2026

12 people who take Centrum and Alrex together, and have interactions are studied.

What are the common drug interactions of Centrum and Alrex, by gender? *:

female:

Intestinal perforation (complete penetration of the wall of the intestine)
Post procedural infection
Asthma
Constipation
Megacolon (a very dilated colon)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Upper respiratory tract infection
Weight decreased
Alopecia (absence of hair from areas of the body)

male:

Ankle fracture
Blood cholesterol increased
Lipoma excision
Oedema (fluid collection in tissue)
Osteoporosis (bones weak and more likely to break)
Pelvic fracture
Pyrexia (fever)
Rib fracture
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Urticaria (rash of round, red welts on the skin that itch intensely)

What are the common drug interactions of Centrum and Alrex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Ankle fracture
Blood cholesterol increased
Bone loss
Bone marrow oedema (inflammation that causes much than the needed fluid in a bone)
Bone pain
Cervical vertebral fracture
Fibromyalgia (a long-term condition which causes pain all over the body)
Fracture
Oedema (fluid collection in tissue)
Osteoporosis (bones weak and more likely to break)

50-59:

Post procedural infection
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Weight decreased
Fibromyalgia (a long-term condition which causes pain all over the body)
Incision site infection (infection at incision site)
Megacolon (a very dilated colon)
Postoperative wound infection
Constipation
Intestinal perforation (complete penetration of the wall of the intestine)

60+:

Alopecia (absence of hair from areas of the body)
Bone pain
Protein urine present
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Injection site pain
Lipoma (a growth of fatty tissue that slowly develops just under your skin)
Lipoma excision
Pain in extremity

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 58.33%
High Blood Pressure: 5 people, 41.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 25.00%
Asthma: 3 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 25.00%
High Blood Cholesterol: 2 people, 16.67%
Eye Disorder: 2 people, 16.67%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 16.67%
Migraine (headache): 2 people, 16.67%
Thyroid Diseases: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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