Centrum and Clinoril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Clinoril (sulindac). Common drug interactions include suicidal ideation among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Clinoril. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Clinoril?

Clinoril has active ingredients of sulindac. eHealthMe is studying from 1,521 Clinoril users. Check the latest studies of Clinoril.

On Jul, 30, 2026

14 people who take Centrum and Clinoril together, and have interactions are studied.

What are the common drug interactions of Centrum and Clinoril, by gender? *:

female:

Suicidal ideation
Swelling face
Tinnitus (a ringing in the ears)
Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances)
Tremor (trembling or shaking movements in one or more parts of your body)
Urticaria (rash of round, red welts on the skin that itch intensely)
Vertigo
Vomiting
Joint injury
Weight increased

male:

Acute respiratory failure
Anaemia (lack of blood)
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Erythema (redness of the skin)
Hemiplegia (paralysis of one side of the body)
Leukocytosis (increased white blood cells)
Limb discomfort (discomfort in leg)
Myositis (inflammation of the muscles)
Oedema peripheral (superficial swelling)

What are the common drug interactions of Centrum and Clinoril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Grip strength decreased
Impaired work ability
Joint injury
Viral infection
Weight increased
Arthropathy

50-59:

Vertigo
Vomiting
Depression
Fall
Abdominal distension
Abdominal pain
Abdominal pain upper
Acute respiratory failure
Affect lability (emotional incontinence)
Agitation (state of anxiety or nervous excitement)

60+:

Drug hypersensitivity
Erythema (redness of the skin)
Burning sensation
Contusion (a type of hematoma of tissue in which capillaries)
Death
Dizziness
Drug ineffective
Dyspepsia (indigestion)
Fall
Haematocrit decreased

What are the existing conditions these people have? *

Pain: 5 people, 35.71%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 28.57%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 21.43%
High Blood Cholesterol: 3 people, 21.43%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 21.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 14.29%
Joint Pain: 2 people, 14.29%
Sleep Disorder: 2 people, 14.29%
Peripheral Swelling: 1 person, 7.14%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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