Centrum and Cod liver oil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Cod liver oil (cod liver oil). Common drug interactions include nasal septum perforation among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Cod liver oil. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Cod liver oil?

Cod liver oil has active ingredients of cod liver oil. It is often used in joint pain. eHealthMe is studying from 3,636 Cod liver oil users. Check the latest studies of Cod liver oil.

On Jul, 17, 2026

85 people who take Centrum and Cod liver oil together, and have interactions are studied.

Centrum and Cod liver oil drug interactions.

What are the common drug interactions of Centrum and Cod Liver Oil, by gender? *:

female:

Nasal septum perforation (hole in nasal septum)
Nausea (feeling of having an urge to vomit)
Nocturia (the need to get up in the night to urinate)
Oedema peripheral (superficial swelling)
Oral disorder (mouth disease)
Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Palpitations (feelings or sensations that your heart is pounding or racing)
Paresis (a condition of muscular weakness)
Petechiae (a small red or purple spot caused by bleeding into the skin)

male:

Diarrhoea
Asthenia (weakness)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Conductive deafness (deafness due to a problem in conducting sound waves)
Confusional state
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery stenosis (narrowing of coronary artery)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)

What are the common drug interactions of Centrum and Cod Liver Oil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Headache (pain in head)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)

40-49:

Aphthous ulcer (mouth ulcer)
Arthropathy
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Bone erosion
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Dysstasia (difficulty in standing)
Femur fracture
Foot fracture
Fracture nonunion (permanent failure of healing following a broken bone)
Hyperkeratosis (thickening of the outer layer of the skin)

50-59:

Somnolence (a state of near-sleep, a strong desire for sleep)
Brain neoplasm (tumour of brain)
Abdominal pain
Depression
Diarrhoea
Feeling jittery
Hypoaesthesia (reduced sense of touch or sensation)
Injection site pain
Insomnia (sleeplessness)
Migraine (headache)

60+:

Dizziness
Asthenia (weakness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Weight decreased
Arthropathy
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dyspnoea exertional (breathlessness or shortness of breath)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 11 people, 12.94%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 9.41%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 8.24%
High Blood Pressure: 7 people, 8.24%
High Blood Cholesterol: 7 people, 8.24%
Immunodeficiency Common Variable: 5 people, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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