Centrum and Dapsone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Dapsone (dapsone). Common drug interactions include white blood cell count decreased among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Dapsone. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Dapsone?

Dapsone has active ingredients of dapsone. It is often used in dermatitis herpetiformis. eHealthMe is studying from 11,732 Dapsone users. Check the latest studies of Dapsone.

On Jul, 09, 2026

93 people who take Centrum and Dapsone together, and have interactions are studied.

What are the common drug interactions of Centrum and Dapsone, by gender? *:

female:

White blood cell count decreased
Alopecia (absence of hair from areas of the body)
Breast cancer
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cough
Full blood count decreased
Influenza
Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
Melanoma recurrent (reoccurrence of tumour of melanocyte)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

male:

Rash
Vomiting
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dyspnoea (difficult or laboured respiration)
Lipase increased
Pain
Pancreatitis acute (sudden inflammation of pancreas)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure (kidney dysfunction)
Anaemia (lack of blood)

What are the common drug interactions of Centrum and Dapsone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal distension
Acidosis (build-up of carbon dioxide in the blood)
Candiduria (candida in urine)
Fungal infection
Hepatic enzyme increased
Hydronephrosis (water inside the kidney)
Injury
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Nephrolithiasis (calculi in the kidneys)
Oedema peripheral (superficial swelling)

40-49:

Adverse drug reaction
Bone pain
Chemotherapy
Dizziness
Drug ineffective
Fungal skin infection
Heparin-induced thrombocytopenia
Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
Neoplasm (tumour)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

50-59:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Catheter site pain
Chest discomfort
Coronary artery bypass
Cough
Death
Diastolic dysfunction
Failure to thrive (inadequate weight gain and physical growth in children)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hepatic neoplasm malignant (liver cancer)

60+:

Neutropenia (an abnormally low number of neutrophils)
Anaemia (lack of blood)
Blood triglycerides increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Lipase increased
Pancreatitis acute (sudden inflammation of pancreas)
Pleural effusion (water on the lungs)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure (kidney dysfunction)
Vomiting

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 40 people, 43.01%
Pain: 9 people, 9.68%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 7 people, 7.53%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 6.45%
Nausea (feeling of having an urge to vomit): 6 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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