Centrum and Depo-testosterone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Depo-testosterone (testosterone cypionate). Common drug interactions include deep vein thrombosis among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Depo-testosterone. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Depo-testosterone?

Depo-testosterone has active ingredients of testosterone cypionate. It is often used in low testosterone. eHealthMe is studying from 4,295 Depo-testosterone users. Check the latest studies of Depo-testosterone.



On Jul, 06, 2026

17 people who take Centrum and Depo-testosterone together, and have interactions are studied.

Centrum and Depo-testosterone drug interactions.

What are the common drug interactions of Centrum and Depo-Testosterone, by gender? *:

female:

n/a

male:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Amino acid level decreased
  3. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  4. Type 2 diabetes mellitus
  5. Acute myocardial infarction (acute heart attack)
  6. Blood pressure increased
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Chest pain
  9. Coronary artery stenosis (narrowing of coronary artery)
  10. Diarrhoea

What are the common drug interactions of Centrum and Depo-Testosterone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Bowel movement irregularity
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Faecal incontinence (a lack of control over passing stool)
  4. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  5. Infection
  6. Mesenteric vein thrombosis (blood clot in mesenteric vein)
  7. Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)

50-59:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Chest pain
  3. Fluid overload (too much fluid in the blood)
  4. Hypotension (abnormally low blood pressure)
  5. Left ventricular dysfunction
  6. Mitral valve incompetence (inefficient heart valve)
  7. Nausea (feeling of having an urge to vomit)
  8. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  9. Pneumonia
  10. Pulmonary congestion (congestion in the lungs)

60+:

  1. Acute myocardial infarction (acute heart attack)
  2. Blood pressure increased
  3. Pulmonary hypertension (increase in blood pressure in the lung artery)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Deafness unilateral
  7. Dry mouth
  8. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  9. Coronary artery stenosis (narrowing of coronary artery)
  10. Diarrhoea

What are the existing conditions these people have? *

  1. Diabetes: 3 people, 17.65%
  2. High Blood Pressure: 3 people, 17.65%
  3. Cardiac Disorder: 3 people, 17.65%
  4. High Blood Cholesterol: 2 people, 11.76%
  5. Multiple Myeloma (cancer of the plasma cells): 2 people, 11.76%
  6. Blood Testosterone Decreased: 2 people, 11.76%
  7. Sleep Disorder: 2 people, 11.76%
  8. Stress And Anxiety: 2 people, 11.76%
  9. B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 1 person, 5.88%
  10. Bleeding Disorders: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Centrum and Depo-testosterone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Centrum and Depo-testosterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Depo-testosterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Centrum and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Depo-testosterone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e and testosterone cypionate (the active ingredients of Centrum and Depo-testosterone, respectively), and Centrum and Depo-testosterone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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