Centrum and Duopa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Duopa (carbidopa; levodopa). Common drug interactions include energy increased among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Duopa. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Duopa?

Duopa has active ingredients of carbidopa; levodopa. eHealthMe is studying from 8,208 Duopa users. Check the latest studies of Duopa.

On Jul, 30, 2026

95 people who take Centrum and Duopa together, and have interactions are studied.

What are the common drug interactions of Centrum and Duopa, by gender? *:

female:

Energy increased
Hallucination (an experience involving the perception of something not present)
Muscle tightness
Procedural pain
Stoma site reaction (reaction at abdominal opening)
Ulcer
Abdominal pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Asthenia (weakness)
Back pain

male:

Fall
Hallucination (an experience involving the perception of something not present)
Freezing phenomenon
Hypotension (abnormally low blood pressure)
Personality change
Ventricular extrasystoles (premature cardiac contraction)
Gait disturbance
Weight decreased
Blood magnesium increased
Drug ineffective

What are the common drug interactions of Centrum and Duopa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cerebrospinal fluid leakage
Spinal fusion surgery

60+:

Fall
Device dislocation
Personality change
Ventricular extrasystoles (premature cardiac contraction)
Device occlusion
Gait disturbance
Dyskinesia (abnormality or impairment of voluntary movement)
Weight decreased
Anxiety
Blood magnesium increased

What are the existing conditions these people have? *

Parkinson's Disease: 57 people, 60.00%
Sleep Disorder: 10 people, 10.53%
Hallucinations (sensations that appear real but are created by your mind): 10 people, 10.53%
Stress And Anxiety: 9 people, 9.47%
High Blood Cholesterol: 8 people, 8.42%
Depression: 7 people, 7.37%
Dyskinesia (abnormality or impairment of voluntary movement): 6 people, 6.32%
Ulcer Haemorrhage (bleeding ulcer): 5 people, 5.26%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 5.26%
Glaucoma (increased fluid pressure in the eye with vision loss): 5 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Centrum and Duopa?

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