Centrum and Skyrizi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Skyrizi (risankizumab-rzaa). Common drug interactions include back pain among females and arterial occlusive disease among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Skyrizi. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Skyrizi?

Skyrizi has active ingredients of risankizumab-rzaa. eHealthMe is studying from 45,385 Skyrizi users. Check the latest studies of Skyrizi.

On Jul, 31, 2026

19 people who take Centrum and Skyrizi together, and have interactions are studied.

What are the common drug interactions of Centrum and Skyrizi, by gender? *:

female:

Back pain
Mobility decreased (ability to move is reduced)
Peripheral swelling
Abdominal distension
Blood pressure increased
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Insomnia (sleeplessness)
Proteinuria (presence of protein in the urine)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)

male:

Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Feeling cold
Neoplasm (tumour)
Pain in extremity
Psoriasis (immune-mediated disease that affects the skin)
Respiratory tract congestion (blockage on respiratory system)
Sinusitis (inflammation of sinus)
Skin discolouration (change of skin colour)
Skin wrinkling (wrinkle on skin)
Upper respiratory tract infection

What are the common drug interactions of Centrum and Skyrizi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal distension
Back pain
Blood pressure increased
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Insomnia (sleeplessness)
Mobility decreased (ability to move is reduced)
Peripheral swelling
Proteinuria (presence of protein in the urine)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal pain
Abdominal pain lower
Blood bilirubin increased
Eye pain
Fallopian tube obstruction (obstruction of fallopian tube)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Paranasal sinus discomfort
Alopecia (absence of hair from areas of the body)
Arrhythmia (irregular heartbeat)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

60+:

Urinary tract infection
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Hydronephrosis (water inside the kidney)
Lung disorder (lung disease)
Respiratory tract congestion (blockage on respiratory system)
Sinusitis (inflammation of sinus)
Upper respiratory tract infection
White blood cell count increased
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blood iron decreased

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 19 people, 100.00%
Pain: 6 people, 31.58%
High Blood Pressure: 5 people, 26.32%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 21.05%
Diabetes: 3 people, 15.79%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 15.79%
Stress And Anxiety: 3 people, 15.79%
Sleep Disorder: 2 people, 10.53%
Hypersensitivity: 2 people, 10.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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