Centrum and Tambocor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Tambocor (flecainide acetate). Common drug interactions include gastrointestinal haemorrhage among females.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Tambocor. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Tambocor?

Tambocor has active ingredients of flecainide acetate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,621 Tambocor users. Check the latest studies of Tambocor.

On Jul, 13, 2026

12 people who take Centrum and Tambocor together, and have interactions are studied.

What are the common drug interactions of Centrum and Tambocor, by gender? *:

female:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Nausea (feeling of having an urge to vomit)
Dizziness
Haematuria present (presence of blood in urine due to trauma)
Haemorrhage (bleeding)
Hair colour changes
Hair disorder
International normalised ratio decreased
Neuropathy peripheral (surface nerve damage)
Pneumonia

male:

n/a

What are the common drug interactions of Centrum and Tambocor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Infection
Haemorrhage (bleeding)
Hair colour changes
Hair disorder
Headache (pain in head)
Hot flush (sudden feelings of heat)
International normalised ratio decreased
Pneumonia
Prothrombin time shortened

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 25.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 16.67%
Senile Osteoporosis (weak bones with ageing): 1 person, 8.33%
Oedema (fluid collection in tissue): 1 person, 8.33%
Hypersensitivity: 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
Dyspnea (difficult or laboured breathing): 1 person, 8.33%
Cardiac Failure Congestive: 1 person, 8.33%
Breast Cancer Female: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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