Centrum and Zioptan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Zioptan (tafluprost). Common drug interactions include dyspnoea among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Zioptan. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Zioptan?

Zioptan has active ingredients of tafluprost. It is often used in glaucoma. eHealthMe is studying from 2,512 Zioptan users. Check the latest studies of Zioptan.

On Jul, 09, 2026

21 people who take Centrum and Zioptan together, and have interactions are studied.

What are the common drug interactions of Centrum and Zioptan, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)
Agitation (state of anxiety or nervous excitement)
Asthenia (weakness)
Back pain
Body height decreased
Cardiac disorder
Constipation
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)

male:

Abdominal pain
Chapped lips (cracking, fissuring, and peeling of the skin f lip)
Pancreatic carcinoma (pancreatic cancer)
Pancreatic mass
Psoriasis (immune-mediated disease that affects the skin)
Erythema (redness of the skin)
Eye disorder
Eye pain
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Incision site erythema (redness of the skin at incision site)

What are the common drug interactions of Centrum and Zioptan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Oral candidiasis (fungal infection of mouth)
Paralysis
Temperature intolerance (inability to go in temperature)
Adverse event
Arterial haemorrhage
Back injury
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Intestinal haemorrhage (bleeding from intestine)
Neck injury
Oesophageal disorder (disease of oesophagus)

60+:

Dyspnoea (difficult or laboured respiration)
Insomnia (sleeplessness)
Constipation
Dementia (madness)
Diarrhoea
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Feeding disorder (when children refuse to eat certain food groups)
Fungal infection
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hypoaesthesia (reduced sense of touch or sensation)

What are the existing conditions these people have? *

High Blood Pressure: 13 people, 61.90%
High Blood Cholesterol: 12 people, 57.14%
Pain: 11 people, 52.38%
Anaemia (lack of blood): 10 people, 47.62%
Diabetes: 10 people, 47.62%
Feeling Of Relaxation: 10 people, 47.62%
Glossitis (infection of tongue with soreness): 10 people, 47.62%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 10 people, 47.62%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 10 people, 47.62%
Ill-Defined Disorder: 10 people, 47.62%

* Approximation only. Some reports may have incomplete information.

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