Cephalexin and Letairis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cephalexin (cephalexin) and Letairis (ambrisentan). Common drug interactions include erythema among females and device failure among males.

The phase IV clinical study analyzes what interactions people have when they take Cephalexin and Letairis. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Cephalexin?

Cephalexin has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 30,581 Cephalexin users. Check the latest studies of Cephalexin.

What is Letairis?

Letairis has active ingredients of ambrisentan. It is often used in pulmonary hypertension. eHealthMe is studying from 94,041 Letairis users. Check the latest studies of Letairis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

77 people who take Cephalexin and Letairis together, and have interactions are studied.

Cephalexin and Letairis drug interactions.

What are the common drug interactions of Cephalexin and Letairis, by gender? *:

female:

Erythema (redness of the skin)
Heart rate increased
Hypersensitivity
Ill-defined disorder
Infusion site infection
Injection site cellulitis (injection site inflammation)
Injection site pain
Lung disorder (lung disease)
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment

male:

Device failure
Asthenia (weakness)
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Blood creatinine increased
Cerumen impaction
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Dermal cyst
Dyspnoea exertional (breathlessness or shortness of breath)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

What are the common drug interactions of Cephalexin and Letairis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Application site hypersensitivity
Application site pain
Application site pruritus (application site severe itching of the skin)
Application site rash
Application site vesicles (small bubble within a cell at application site)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Catheter site cellulitis (infection of cells near catheter)
Catheter site erythema (redness of skin at catheter site)
Catheter site haemorrhage (bleeding at catheter site)
Catheter site pain

20-29:

n/a

30-39:

Myalgia (muscle pain)
Pain
Pain in extremity
Productive cough
Pyrexia (fever)
Rash
Swelling
Vision blurred
Device failure
Headache (pain in head)

40-49:

Asthenia (weakness)
Influenza
Myalgia (muscle pain)
Oropharyngeal pain
Speech disorder
Dizziness
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Dehydration (dryness resulting from the removal of water)
Gastric infection (infection of stomach)

50-59:

Dyspnoea (difficult or laboured respiration)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Oedema peripheral (superficial swelling)
Anaemia (lack of blood)
Cardiac failure congestive
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Skin ulcer
Blood iron decreased

60+:

Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Blood creatinine increased
Chest pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fluid overload (too much fluid in the blood)
Hip arthroplasty
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 51 people, 66.23%

* Approximation only. Some reports may have incomplete information.

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