Cephalexin and Renagel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cephalexin (cephalexin) and Renagel (sevelamer hydrochloride). Common drug interactions include atrial fibrillation among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Cephalexin and Renagel. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Cephalexin?

Cephalexin has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 30,580 Cephalexin users. Check the latest studies of Cephalexin.

What is Renagel?

Renagel has active ingredients of sevelamer hydrochloride. eHealthMe is studying from 8,246 Renagel users. Check the latest studies of Renagel.



On Aug, 07, 2026

83 people who take Cephalexin and Renagel together, and have interactions are studied.

Cephalexin and Renagel drug interactions.

What are the common drug interactions of Cephalexin and Renagel, by gender? *:

female:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Pain
  3. Pain in extremity
  4. Anxiety
  5. Dyspnoea exertional (breathlessness or shortness of breath)
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Hypertension (high blood pressure)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Mobility decreased (ability to move is reduced)
  10. Muscular weakness (muscle weakness)

male:

  1. Pain
  2. Renal failure (kidney dysfunction)
  3. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  4. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  5. Oedema peripheral (superficial swelling)
  6. Peau d'orange (orange peel skin)
  7. Pigmentation disorder (disturbances of human skin colour)
  8. Renal failure chronic (long lasting kidney dysfunction)
  9. Skin disorder (skin disease)
  10. Skin exfoliation (removal of the oldest dead skin cells)

What are the common drug interactions of Cephalexin and Renagel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Renal failure (kidney dysfunction)
  2. Cardiac failure congestive
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  6. Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
  7. Hypertension (high blood pressure)
  8. Nephrolithiasis (calculi in the kidneys)
  9. Cholecystitis chronic (long lasting infection of gallbladder)
  10. Anhedonia (inability to experience pleasure from activities usually found enjoyable)

30-39:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

40-49:

  1. Renal failure (kidney dysfunction)
  2. Chronic kidney disease
  3. Emotional distress
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Anxiety
  6. Dyspnoea (difficult or laboured respiration)
  7. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  8. Pain
  9. Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
  10. Tooth loss

50-59:

  1. Nausea (feeling of having an urge to vomit)
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  3. Weight decreased
  4. Gait disturbance
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Mobility decreased (ability to move is reduced)
  7. Muscular weakness (muscle weakness)
  8. Oedema peripheral (superficial swelling)
  9. Pain in extremity
  10. Adrenal neoplasm (abnormal growth of adrenal gland)

60+:

  1. Renal failure chronic (long lasting kidney dysfunction)
  2. Asthenia (weakness)
  3. Peau d'orange (orange peel skin)
  4. Pigmentation disorder (disturbances of human skin colour)
  5. Rash
  6. Skin disorder (skin disease)
  7. Skin exfoliation (removal of the oldest dead skin cells)
  8. Skin hypertrophy (skin cells enlarges)
  9. Skin induration (an abnormally hard spot or area on the skin)
  10. Skin tightness

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 19 people, 22.89%
  2. High Blood Cholesterol: 18 people, 21.69%
  3. Pain: 17 people, 20.48%
  4. High Blood Pressure: 16 people, 19.28%
  5. Multiple Myeloma (cancer of the plasma cells): 12 people, 14.46%
  6. Light Chain Analysis Increased: 12 people, 14.46%
  7. Blood Pressure Abnormal: 7 people, 8.43%
  8. Cardiac Failure Congestive: 7 people, 8.43%
  9. Depression: 7 people, 8.43%
  10. Stress And Anxiety: 7 people, 8.43%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cephalexin and Renagel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cephalexin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Renagel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cephalexin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Renagel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cephalexin and sevelamer hydrochloride (the active ingredients of Cephalexin and Renagel, respectively), and Cephalexin and Renagel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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