Cerezyme and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cerezyme (imiglucerase) and Keppra (levetiracetam). Common drug interactions include vocal cord disorder among females and convulsion among males.

The phase IV clinical study analyzes what interactions people have when they take Cerezyme and Keppra. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Cerezyme?

Cerezyme has active ingredients of imiglucerase. eHealthMe is studying from 6,451 Cerezyme users. Check the latest studies of Cerezyme.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

On Aug, 04, 2026

28 people who take Cerezyme and Keppra together, and have interactions are studied.

What are the common drug interactions of Cerezyme and Keppra, by gender? *:

female:

Vocal cord disorder
White blood cell count increased
Back pain
Fatigue (feeling of tiredness)
Hypersomnia (excessive daytime sleepiness (eds))
Micturition disorder (disease of passing urine)
Pain in extremity
Poor quality sleep
Stress
Tongue biting

male:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Cytomegalovirus test positive
Dysarthria (speech disorder)
Gait disturbance
Hemiparesis (weakness on one side of the body)
Incontinence (lack of moderation or self-control)
Neurological decompensation (inability of brain to maintain proper function)
Pneumonia
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Cerezyme and Keppra, by age (0-1 to 60+)? *:

0-1:

Cytomegalovirus test positive
Brain stem syndrome
Disease progression
Sudden death

2-9:

Death
Hypersensitivity
Hypotension (abnormally low blood pressure)
Inflammation
Peripheral coldness
Pyrexia (fever)
Septic shock (shock due to blood infection)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

10-19:

Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Fall
Tremor (trembling or shaking movements in one or more parts of your body)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Loss of consciousness
Vomiting
Activities of daily living impaired
Areflexia (absence of a reflex)
Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)

20-29:

Micturition disorder (disease of passing urine)
Pain in extremity
Poor quality sleep
Stress
Tongue biting
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Hemiparesis (weakness on one side of the body)
Spinal fusion surgery
Ascites (accumulation of fluid in the abdominal cavity)
Bone density decreased

30-39:

Eye irritation
Nephrolithiasis (calculi in the kidneys)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Crying
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Mass
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 7.14%
Muscle Spasms (muscle contraction): 2 people, 7.14%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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