Cetamide and Tramadol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cetamide (sulfacetamide sodium) and Tramadol (tramadol hydrochloride). Common drug interactions include flatulence among females and amyotrophy among males.

The phase IV clinical study analyzes what interactions people have when they take Cetamide and Tramadol. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Cetamide?

Cetamide has active ingredients of sulfacetamide sodium. eHealthMe is studying from 1,053 Cetamide users. Check the latest studies of Cetamide.

What is Tramadol?

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 235,800 Tramadol users. Check the latest studies of Tramadol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 16, 2026

59 people who take Cetamide and Tramadol together, and have interactions are studied.

Cetamide and Tramadol drug interactions.

What are the common drug interactions of Cetamide and Tramadol, by gender? *:

female:

  1. Flatulence (flatus expelled through the anus)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Heart rate increased
  4. Hypersomnia (excessive daytime sleepiness (eds))
  5. Injury
  6. Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
  7. Multiple fractures
  8. Neck pain
  9. Nephropathy (damage to or disease of a kidney)
  10. Osteoporosis (bones weak and more likely to break)

male:

  1. Amyotrophy (muscular wasting or atrophy)
  2. Depression
  3. Sinusitis (inflammation of sinus)
  4. Infusion related reaction
  5. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  6. Multiple allergies (allergy to multiple agents)
  7. Nasopharyngitis (inflammation of the nasopharynx)
  8. Nausea (feeling of having an urge to vomit)
  9. Arthralgia (joint pain)
  10. Asthenia (weakness)

What are the common drug interactions of Cetamide and Tramadol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Atelectasis (partial or complete collapse of the lung)
  2. Chest discomfort
  3. Chest pain
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Dyspnoea (difficult or laboured respiration)
  6. Injury
  7. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  8. Pulmonary embolism (blockage of the main artery of the lung)

20-29:

n/a

30-39:

  1. Abdominal adhesions (inflammation of abdomen)
  2. Abdominal pain
  3. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  4. Anaemia (lack of blood)
  5. Blood pressure increased
  6. Bowel movement irregularity
  7. Cold sweat
  8. Constipation
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  10. Depression

40-49:

  1. Chronic kidney disease
  2. Erythema (redness of the skin)
  3. Pruritus (severe itching of the skin)
  4. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  5. Gastric cancer (stomach cancer)
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Hypertension (high blood pressure)
  8. Nephrogenic anaemia (anaemia due to kidney disease)
  9. Nephropathy (damage to or disease of a kidney)
  10. Renal failure (kidney dysfunction)

50-59:

  1. Pneumonia primary atypical (primary atypical pneumonia which were probably caused by mycoplasma pneumoniae)
  2. Prothrombin time shortened
  3. Pulmonary congestion (congestion in the lungs)
  4. Pulmonary granuloma (tiny lump of inflamed tissue in the lungs)
  5. Pulmonary haemorrhage (acute bleeding from the lung)
  6. Pulmonary infarction (death of a small area of lung)
  7. Pulmonary sarcoidosis (growth of tiny collections of inflammatory cells in lungs)
  8. Pyrexia (fever)
  9. Renal injury (kidney injury)
  10. Respiratory rate increased (excess breathing rate/min)

60+:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Secretion discharge
  4. Sinusitis (inflammation of sinus)
  5. Chronic kidney disease
  6. Nausea (feeling of having an urge to vomit)
  7. Renal failure (kidney dysfunction)
  8. Arthralgia (joint pain)
  9. Asthenia (weakness)
  10. Bowel movement irregularity

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 23.73%
  2. High Blood Cholesterol: 10 people, 16.95%
  3. High Blood Pressure: 10 people, 16.95%
  4. Depression: 10 people, 16.95%
  5. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 9 people, 15.25%
  6. Gastric Ulcer (stomach ulcer): 7 people, 11.86%
  7. Stress And Anxiety: 7 people, 11.86%
  8. Nausea (feeling of having an urge to vomit): 6 people, 10.17%
  9. Hypersensitivity: 6 people, 10.17%
  10. Neuralgia (pain in one or more nerves): 6 people, 10.17%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cetamide and Tramadol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cetamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tramadol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cetamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tramadol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sulfacetamide sodium and tramadol hydrochloride (the active ingredients of Cetamide and Tramadol, respectively), and Cetamide and Tramadol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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