Cevimeline and Ketoconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cevimeline (cevimeline hydrochloride) and Ketoconazole (ketoconazole). Common drug interactions include chronic kidney disease among females and malaise among males.

The phase IV clinical study analyzes what interactions people have when they take Cevimeline and Ketoconazole. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Cevimeline?

Cevimeline has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 1,480 Cevimeline users. Check the latest studies of Cevimeline.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

On Jul, 15, 2026

14 people who take Cevimeline and Ketoconazole together, and have interactions are studied.

Cevimeline and Ketoconazole drug interactions.

What are the common drug interactions of Cevimeline and Ketoconazole, by gender? *:

female:

Chronic kidney disease
Insomnia (sleeplessness)
Restlessness (not able to rest)
Asthenia (weakness)
Chest pain
Cough
Drug intolerance (drug sensitivity)
Dyspnoea (difficult or laboured respiration)
Eye pain
Fatigue (feeling of tiredness)

male:

Malaise (a feeling of general discomfort or uneasiness)
Abdominal discomfort
Nephrolithiasis (calculi in the kidneys)
Paralysis
Peripheral swelling
Somnolence (a state of near-sleep, a strong desire for sleep)
Swelling face
Urinary tract infection
Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Cevimeline and Ketoconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal discomfort
Dyspnoea (difficult or laboured respiration)
Epistaxis (bleed from the nose)
Eye discharge
Injection site bruising
Muscle spasms (muscle contraction)
Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

n/a

50-59:

Hypoacusis (loss of hearing)
Immune system disorder
Influenza
Nasopharyngitis (inflammation of the nasopharynx)
Pain
Vision blurred
Chronic kidney disease
Asthenia (weakness)
Chest pain
Cough

60+:

Malaise (a feeling of general discomfort or uneasiness)
Leukaemia (blood or bone marrow cancer)

What are the existing conditions these people have? *

Dry Mouth: 3 people, 21.43%
Type 2 Diabetes: 2 people, 14.29%
Pain: 2 people, 14.29%
Stress And Anxiety: 2 people, 14.29%
High Blood Cholesterol: 2 people, 14.29%
Tardive Dyskinesia (a disorder that involves involuntary movements): 2 people, 14.29%
Depression: 2 people, 14.29%
High Blood Pressure: 2 people, 14.29%
Asthma: 2 people, 14.29%
Vitamin B12 Deficiency: 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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