Cevimeline and Nuvigil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cevimeline (cevimeline hydrochloride) and Nuvigil (armodafinil). Common drug interactions include panic attack among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Cevimeline and Nuvigil. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Cevimeline?

Cevimeline has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 1,480 Cevimeline users. Check the latest studies of Cevimeline.

What is Nuvigil?

Nuvigil has active ingredients of armodafinil. It is often used in narcolepsy. eHealthMe is studying from 23,669 Nuvigil users. Check the latest studies of Nuvigil.

On Jul, 28, 2026

52 people who take Cevimeline and Nuvigil together, and have interactions are studied.

Cevimeline and Nuvigil drug interactions.

What are the common drug interactions of Cevimeline and Nuvigil, by gender? *:

female:

Panic attack
Accident
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood copper increased
Chest pain
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Facial bones fracture (bone fracture of face)
Feeling jittery
Herpes zoster

male:

Diarrhoea
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Cevimeline and Nuvigil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Bipolar disorder (mood disorder)
Blood pressure increased
Chest pain
Confusional state
Nausea (feeling of having an urge to vomit)
Panic attack
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Psychotic disorder

30-39:

n/a

40-49:

Hyperlipidaemia (presence of excess lipids in the blood)
Nasal septum deviation (deviated nasal septum)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Upper respiratory tract infection

50-59:

Malaise (a feeling of general discomfort or uneasiness)
Anxiety
Blood copper increased
Blood pressure increased
Feeling jittery
Intervertebral disc protrusion (spinal disc protrusion)
Panic attack
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Therapeutic response unexpected
Abnormal sleep-related event

60+:

Nausea (feeling of having an urge to vomit)
Hospitalisation
Drug ineffective
Fall
Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)
Respiratory failure (inadequate gas exchange by the respiratory system)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Nasopharyngitis (inflammation of the nasopharynx)
Norovirus test positive
Respiratory tract congestion (blockage on respiratory system)

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 22 people, 42.31%
Drowsiness: 6 people, 11.54%
Hyperkalemia (damage to or disease of the kidney): 5 people, 9.62%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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