Chantix and Methadose drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chantix (varenicline tartrate) and Methadose (methadone hydrochloride). Common drug interactions include abnormal dreams among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Chantix and Methadose. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Chantix?

Chantix has active ingredients of varenicline tartrate. It is often used in quit smoking. eHealthMe is studying from 89,889 Chantix users. Check the latest studies of Chantix.

What is Methadose?

Methadose has active ingredients of methadone hydrochloride. It is often used in pain. eHealthMe is studying from 5,101 Methadose users. Check the latest studies of Methadose.

On Aug, 10, 2026

14 people who take Chantix and Methadose together, and have interactions are studied.

Chantix and Methadose drug interactions.

What are the common drug interactions of Chantix and Methadose, by gender? *:

female:

Abnormal dreams
Anxiety
Depression
Hallucination (an experience involving the perception of something not present)
Insomnia (sleeplessness)
Joint dislocation (a joint position is changed from normal position)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Road traffic accident
Schizoaffective disorder (a mental disorder characterized by disordered thought)
Suicidal behaviour

male:

Anxiety
Cardiac arrest
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Nocturia (the need to get up in the night to urinate)
Oedema peripheral (superficial swelling)
Overdose
Pain in extremity
Sleep disorder

What are the common drug interactions of Chantix and Methadose, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain upper
Anxiety
Chest pain
Chronic kidney disease
Depression
Diplopia (double vision)
Dizziness
Dyspepsia (indigestion)
Influenza
Joint swelling

50-59:

Abnormal dreams
Suicidal behaviour
Syncope (loss of consciousness with an inability to maintain postural tone)
Anxiety
Depression
Hallucination (an experience involving the perception of something not present)
Insomnia (sleeplessness)
Joint dislocation (a joint position is changed from normal position)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Road traffic accident

60+:

Injury

What are the existing conditions these people have? *

Depression: 6 people, 42.86%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 42.86%
High Blood Cholesterol: 5 people, 35.71%
Hypersensitivity: 5 people, 35.71%
Headache (pain in head): 5 people, 35.71%
Stress And Anxiety: 5 people, 35.71%
Anticonvulsant Drug Level Increased: 4 people, 28.57%
Back Pain: 4 people, 28.57%
Bipolar Disorder (mood disorder): 4 people, 28.57%
Cough: 4 people, 28.57%

* Approximation only. Some reports may have incomplete information.

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