Chantix and Vascepa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chantix (varenicline tartrate) and Vascepa (icosapent ethyl). Common drug interactions include nausea among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Chantix and Vascepa. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Chantix?

Chantix has active ingredients of varenicline tartrate. It is often used in quit smoking. eHealthMe is studying from 89,889 Chantix users. Check the latest studies of Chantix.

What is Vascepa?

Vascepa has active ingredients of icosapent ethyl. It is often used in high blood cholesterol. eHealthMe is studying from 5,894 Vascepa users. Check the latest studies of Vascepa.

On Aug, 07, 2026

16 people who take Chantix and Vascepa together, and have interactions are studied.

What are the common drug interactions of Chantix and Vascepa, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Abnormal dreams
Back pain
Blood glucose fluctuation
Bone pain
Chronic kidney disease
Crying
Decreased appetite
Dizziness
Dyspnoea (difficult or laboured respiration)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Mass
Osteoporosis (bones weak and more likely to break)
Radius fracture
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dizziness
Fatigue (feeling of tiredness)
Loss of consciousness
Renal failure (kidney dysfunction)

What are the common drug interactions of Chantix and Vascepa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Chronic kidney disease
Emotional distress
Fall
Grip strength decreased
Joint range of motion decreased (disease of joint movement)
Mass
Osteopenia (a condition where bone mineral density is lower than normal)

50-59:

Dizziness
Dyspnoea (difficult or laboured respiration)
Epistaxis (bleed from the nose)
Fibromyalgia (a long-term condition which causes pain all over the body)
Fluid retention (an abnormal accumulation of fluid in the blood)
Hallucination (an experience involving the perception of something not present)
Headache (pain in head)
Hypertension (high blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Insomnia (sleeplessness)

60+:

Chronic kidney disease
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Fatigue (feeling of tiredness)
Sleep disorder

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 25.00%
Hiv Infection: 4 people, 25.00%
Hypersensitivity: 2 people, 12.50%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 12.50%
Pain: 2 people, 12.50%
High Blood Pressure: 2 people, 12.50%
Cardiac Disorder: 1 person, 6.25%
Blood Pressure Abnormal: 1 person, 6.25%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 6.25%
Blood Calcium Decreased: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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