Charcoal and Midazolam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Charcoal (activated charcoal) and Midazolam (midazolam). Common drug interactions include metabolic acidosis among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Charcoal and Midazolam. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Charcoal?

Charcoal has active ingredients of activated charcoal. eHealthMe is studying from 1,179 Charcoal users. Check the latest studies of Charcoal.

What is Midazolam?

Midazolam has active ingredients of midazolam. eHealthMe is studying from 11,246 Midazolam users. Check the latest studies of Midazolam.

On Jul, 07, 2026

22 people who take Charcoal and Midazolam together, and have interactions are studied.

Charcoal and Midazolam drug interactions.

What are the common drug interactions of Charcoal and Midazolam, by gender? *:

female:

Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Drug ineffective
Cardiac arrest
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Bradycardia (abnormally slow heart action)
Hypotension (abnormally low blood pressure)
Suicide attempt
Alanine aminotransferase increased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

male:

Drug ineffective
Drug abuse
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Suicide attempt
Agitation (state of anxiety or nervous excitement)
Cardiac arrest
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Renal injury (kidney injury)
Ventricular fibrillation (abnormally irregular heart rhythm)

What are the common drug interactions of Charcoal and Midazolam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cardiac arrest
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Alanine aminotransferase increased
Bradycardia (abnormally slow heart action)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiogenic shock (inadequate circulation of blood)
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
Coma (state of unconsciousness lasting more than six hours)
Diastolic dysfunction

20-29:

Drug abuse
Drug ineffective
Cardiac arrest
Hypotension (abnormally low blood pressure)
Renal injury (kidney injury)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Ventricular fibrillation (abnormally irregular heart rhythm)

30-39:

Drug ineffective
Hepatic failure (liver failure)
Lactic acidosis (low ph in body tissues)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Suicide attempt
Agitation (state of anxiety or nervous excitement)
Drug abuse
Headache (pain in head)

40-49:

Drug ineffective
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)

50-59:

Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances)
Bradycardia (abnormally slow heart action)
Drug abuse
Drug intolerance (drug sensitivity)
Hypotension (abnormally low blood pressure)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
Suicide attempt

60+:

Drug ineffective
Suicide attempt

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 36.36%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 5 people, 22.73%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 5 people, 22.73%
Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 18.18%
Suicide Attempt: 4 people, 18.18%
Overdose: 4 people, 18.18%
Cardiac Arrest: 4 people, 18.18%
Hypotension (abnormally low blood pressure): 3 people, 13.64%
Depression: 3 people, 13.64%
Ventricular Fibrillation (abnormally irregular heart rhythm): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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