Chlorhexidine gluconate and Prograf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chlorhexidine gluconate (chlorhexidine gluconate) and Prograf (tacrolimus). Common drug interactions include gastrooesophageal reflux disease among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Chlorhexidine gluconate and Prograf. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Chlorhexidine gluconate?

Chlorhexidine gluconate has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 8,233 Chlorhexidine gluconate users. Check the latest studies of Chlorhexidine gluconate.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

On Jul, 13, 2026

31 people who take Chlorhexidine gluconate and Prograf together, and have interactions are studied.

Chlorhexidine gluconate and Prograf drug interactions.

What are the common drug interactions of Chlorhexidine Gluconate and Prograf, by gender? *:

female:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Magnesium deficiency (lack of magnesium)
Vitamin d deficiency
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Skin lesion
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Device related infection
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)

male:

Pneumonia
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Renal failure (kidney dysfunction)
Rotator cuff repair
Spinal cord injury
Upper limb fracture
Hypoxia (low oxygen in tissues)

What are the common drug interactions of Chlorhexidine Gluconate and Prograf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pericardial effusion (fluid around the heart)

20-29:

n/a

30-39:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Blood creatinine increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Disease progression
Febrile neutropenia (fever with reduced white blood cells)
Hyperamylasaemia (acute pancreatitis in which serum amylase is usually elevated more than 4-fold)
Nausea (feeling of having an urge to vomit)
Renal impairment (severely reduced kidney function)
Stomatitis (inflammation of mucous membrane of mouth)

40-49:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Skin lesion
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Device related infection
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bone density decreased
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Chronic kidney disease

50-59:

Respiratory failure (inadequate gas exchange by the respiratory system)
Acute respiratory failure
Anaemia (lack of blood)
Blood bilirubin increased
Body temperature increased
Cardiac failure congestive
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Fluid overload (too much fluid in the blood)
Fluid retention (an abnormal accumulation of fluid in the blood)
Haemorrhage (bleeding)

60+:

Dyspnoea (difficult or laboured respiration)
Adenovirus infection
Hypoxia (low oxygen in tissues)
Interstitial lung disease
Metastases to chest wall (cancer spreads to chest wall)
Metastases to lung (cancer spreads to lung)
Metastases to lymph nodes (cancer spreads to lymph node)
Muscle twitching
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

Diabetes: 4 people, 12.90%
Hiv Infection: 3 people, 9.68%
Stress And Anxiety: 2 people, 6.45%
Hypokalemia (low potassium): 2 people, 6.45%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 6.45%
Cough: 2 people, 6.45%
Depression: 2 people, 6.45%
Diarrhea: 2 people, 6.45%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.45%
High Blood Pressure: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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